The Administrative Core will be responsible for integrating all scientific and infrastructure activities of the Conte Center. Drs. Robert Schwarcz (the Center PI and co-PI of the Core) and William Carpenter (co-PI of the Core), together with the Steering Committee, will have overall responsibility for all administrative functions of the Center. The Steering Committee will include the key scientific leadership for this application: Dr. L. Tonelli (PI, Project 2);Dr. L.E. Hong (PI, Project 3);Dr. R.W. Buchanan (PI, Project 4);Dr. R. McMahon (Biostatistician);and Dr. J. Gold (Neuropsychologist), and will meet monthly to review the progress of each of the projects. They will also review the Biostatistics and Data Management Module, which provides statistical and data base support for the projects. In consultation with NIMH program staff, the Core will establish an External Advisory Committee and consult/meet with the advisors regulariy to review plans. The External Advisory Committee will include experts in relevant translafional neuroscience, clinical research and drug discovery academic and industry labs. The Steering Committee will also be directly involved in: review of proposals for Pilot and Feasibility projects;facilitating the involvement of post- doctoral research fellows and junior faculty in Center activities;involving all Center scientific staff in Center progress through an annual retreat;overseeing training in responsible conduct of research and HIPAA regulations, diversity recruitment;overseeing compliance with UMB and Federal Human Subjects and Vertebrate Animals regulations;implementation of an Optional Summer Research Experience for undergraduates;dissemination of research results and sharing of research data;and coordinating the provision of staff support [funded by the host institution (MPRC) rather than this grant] for administrative functions of the Center;data management and data entry;and IT staff, as well as IT hardware and software resources.

Public Health Relevance

The Administrative Core will be responsible for the close oversight and optimal integration of all planned Conte Center activities. Led by experienced investigators. Core personnel will facilitate investigator interactions and productivity, internal and external educational projects related to Center science, and relations with regulatory groups. ^

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
1P50MH103222-01
Application #
8816206
Study Section
Special Emphasis Panel (ZMH1-ERB-L (01))
Project Start
Project End
Budget Start
2014-05-09
Budget End
2015-04-30
Support Year
1
Fiscal Year
2014
Total Cost
$429,200
Indirect Cost
$149,591
Name
University of Maryland Baltimore
Department
Type
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Song, Chang; Clark, Sarah M; Vaughn, Chloe N et al. (2018) Quantitative Analysis of Kynurenine Aminotransferase II in the Adult Rat Brain Reveals High Expression in Proliferative Zones and Corpus Callosum. Neuroscience 369:1-14
Chiappelli, Joshua; Notarangelo, Francesca M; Pocivavsek, Ana et al. (2018) Influence of plasma cytokines on kynurenine and kynurenic acid in schizophrenia. Neuropsychopharmacology 43:1675-1680
van Erp, Theo G M; Walton, Esther; Hibar, Derrek P et al. (2018) Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biol Psychiatry 84:644-654
Pocivavsek, Ana; Rowland, Laura M (2018) Basic Neuroscience Illuminates Causal Relationship Between Sleep and Memory: Translating to Schizophrenia. Schizophr Bull 44:7-14
Hahn, Britta; Reneski, Carolyn H; Pocivavsek, Ana et al. (2018) Prenatal kynurenine treatment in rats causes schizophrenia-like broad monitoring deficits in adulthood. Psychopharmacology (Berl) 235:651-661
Kelly, Deanna L; Li, Xin; Kilday, Catherine et al. (2018) Increased circulating regulatory T cells in medicated people with schizophrenia. Psychiatry Res 269:517-523
Puvvada, Krishna C; Summerfelt, Ann; Du, Xiaoming et al. (2018) Delta Vs Gamma Auditory Steady State Synchrony in Schizophrenia. Schizophr Bull 44:378-387
Chiappelli, Joshua; Chen, Shuo; Hackman, Ann et al. (2018) Evidence for differential opioid use disorder in schizophrenia in an addiction treatment population. Schizophr Res 194:26-31
Ryan, Meghann C; Kochunov, Peter; Sherman, Paul M et al. (2018) Miniature pig magnetic resonance spectroscopy model of normal adolescent brain development. J Neurosci Methods 308:173-182
Chiappelli, Joshua; Rowland, Laura M; Notarangelo, Francesca M et al. (2018) Salivary kynurenic acid response to psychological stress: inverse relationship to cortical glutamate in schizophrenia. Neuropsychopharmacology 43:1706-1711

Showing the most recent 10 out of 78 publications