Abstract

This core will provide the necessary tools to analyze the data from experiments proposed in Projects 1 through 3. This will involve achieving the following aims. First, the existing voxel-level ANOVA will be thoroughly validated for the experiments proposed here and will be extended to include sub-ANOVAs for the analysis of interaction terms. Second, repression analysis will be implemented for post hoc comparisons for block design experiments. Third, flat mapping software will be integrated into our display and analysis package, and finally, a number of methods will be implemented and tested to support the goals of specific experiments.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
5P50NS006833-35
Application #
6449046
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
2001-03-01
Project End
2002-02-28
Budget Start
Budget End
Support Year
35
Fiscal Year
2001
Total Cost
$288,255
Indirect Cost

  Institution

Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Goyal, Manu S; Vlassenko, Andrei G; Blazey, Tyler M et al. (2017) Loss of Brain Aerobic Glycolysis in Normal Human Aging. Cell Metab 26:353-360.e3
Shannon, Benjamin J; Vaishnavi, Sanjeev Neil; Vlassenko, Andrei G et al. (2016) Brain aerobic glycolysis and motor adaptation learning. Proc Natl Acad Sci U S A 113:E3782-91
Wig, Gagan S; Laumann, Timothy O; Cohen, Alexander L et al. (2014) Parcellating an individual subject's cortical and subcortical brain structures using snowball sampling of resting-state correlations. Cereb Cortex 24:2036-54
Goyal, Manu S; Hawrylycz, Michael; Miller, Jeremy A et al. (2014) Aerobic glycolysis in the human brain is associated with development and neotenous gene expression. Cell Metab 19:49-57
Powers, William J (2014) William M. Feinberg award for excellence in clinical stroke: hemodynamics and stroke risk in carotid artery occlusion. Stroke 45:3123-8
Glasser, Matthew F; Goyal, Manu S; Preuss, Todd M et al. (2014) Trends and properties of human cerebral cortex: correlations with cortical myelin content. Neuroimage 93 Pt 2:165-75
Power, Jonathan D; Mitra, Anish; Laumann, Timothy O et al. (2014) Methods to detect, characterize, and remove motion artifact in resting state fMRI. Neuroimage 84:320-41
Duchek, Janet M; Balota, David A; Thomas, Jewell B et al. (2013) Relationship between Stroop performance and resting state functional connectivity in cognitively normal older adults. Neuropsychology 27:516-28
Wang, Liang; Brier, Matthew R; Snyder, Abraham Z et al. (2013) Cerebrospinal fluid A?42, phosphorylated Tau181, and resting-state functional connectivity. JAMA Neurol 70:1242-8
Shannon, B J; Dosenbach, R A; Su, Y et al. (2013) Morning-evening variation in human brain metabolism and memory circuits. J Neurophysiol 109:1444-56

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