Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
5P50NS012587-21
Application #
2262452
Study Section
Special Emphasis Panel (SRC (06))
Project Start
1979-04-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
21
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Neurosurgery
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Kleindienst, Andrea; Dunbar, Jana G; Glisson, Renee et al. (2013) The role of vasopressin V1A receptors in cytotoxic brain edema formation following brain injury. Acta Neurochir (Wien) 155:151-64
Brophy, Gretchen M; Mazzeo, Anna Teresa; Brar, Satjit et al. (2013) Exposure of cyclosporin A in whole blood, cerebral spinal fluid, and brain extracellular fluid dialysate in adults with traumatic brain injury. J Neurotrauma 30:1484-9
Prieto, Ruth; Tavazzi, Barbara; Taya, Keisuke et al. (2011) Brain energy depletion in a rodent model of diffuse traumatic brain injury is not prevented with administration of sodium lactate. Brain Res 1404:39-49
Fazzina, Giovanna; Amorini, Angela M; Marmarou, Christina R et al. (2010) The protein kinase C activator phorbol myristate acetate decreases brain edema by aquaporin 4 downregulation after middle cerebral artery occlusion in the rat. J Neurotrauma 27:453-61
Mazzeo, Anna Teresa; Brophy, Gretchen M; Gilman, Charlotte B et al. (2009) Safety and tolerability of cyclosporin a in severe traumatic brain injury patients: results from a prospective randomized trial. J Neurotrauma 26:2195-206
Fabricius, Martin; Fuhr, Susanne; Willumsen, Lisette et al. (2008) Association of seizures with cortical spreading depression and peri-infarct depolarisations in the acutely injured human brain. Clin Neurophysiol 119:1973-84
Mazzeo, Anna Teresa; Alves, Oscar Luis; Gilman, Charlotte B et al. (2008) Brain metabolic and hemodynamic effects of cyclosporin A after human severe traumatic brain injury: a microdialysis study. Acta Neurochir (Wien) 150:1019-31;discussion 1031
Lu, J; Marmarou, A; Choi, S et al. (2005) Mortality from traumatic brain injury. Acta Neurochir Suppl 95:281-5
Tavazzi, Barbara; Signoretti, Stefano; Lazzarino, Giuseppe et al. (2005) Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats. Neurosurgery 56:582-9; discussion 582-9
Signoretti, Stefano; Marmarou, Anthony; Tavazzi, Barbara et al. (2004) The protective effect of cyclosporin A upon N-acetylaspartate and mitochondrial dysfunction following experimental diffuse traumatic brain injury. J Neurotrauma 21:1154-67

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