Center for Narcolepsy and Related Disorders (PSO) The Core essentially coordinates activities across the three projects and coordinates the banking of human samples for research on human narcolepsy, a disorder affecting 150,000 to 200,000 Americans. To support this research and research funded by other grants within the Center for Narcolepsy, three main core activities are recognized: (1) An administrative and coordinating function to facilitate research and interactions among investigators and projects (2) Recruitment of human narcolepsy patients for research projects;this includes the banking of DNA, CSF, throat swabs, and brain specimens from narcolepsy and control subjects. Recruitment will focus on recent onset. (3) Maintenance of computerized databases containing human clinical data, DNA, serum, and CSF samples.
The Core provides support for this multidisciplinary program project focusing on human narcolepsy, a disorder affecting 150,000-250,000 Americans. To support this research the personnel in the Core administers and co-ordinates research activities, recruits human narcolepsy patients and controls for DNA samples and maintains the database housing the information from these samples.
Bonvalet, Melodie; Ollila, Hanna M; Ambati, Aditya et al. (2017) Autoimmunity in narcolepsy. Curr Opin Pulm Med 23:522-529 |
Plante, David T; Finn, Laurel A; Hagen, Erika W et al. (2016) Subjective and Objective Measures of Hypersomnolence Demonstrate Divergent Associations with Depression among Participants in the Wisconsin Sleep Cohort Study. J Clin Sleep Med 12:571-8 |
Gottlieb, D J; Hek, K; Chen, T-H et al. (2015) Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. Mol Psychiatry 20:1232-9 |
Ollila, Hanna M; Ravel, Jean-Marie; Han, Fang et al. (2015) HLA-DPB1 and HLA class I confer risk of and protection from narcolepsy. Am J Hum Genet 96:136-46 |
Li, Jason; Moore 4th, Hyatt; Lin, Ling et al. (2015) Association of low ferritin with PLM in the Wisconsin Sleep Cohort. Sleep Med 16:1413-1418 |
Kornum, Birgitte Rahbek; Pizza, Fabio; Knudsen, Stine et al. (2015) Cerebrospinal fluid cytokine levels in type 1 narcolepsy patients very close to onset. Brain Behav Immun 49:54-8 |
Kawai, Makoto; O'Hara, Ruth; Einen, Mali et al. (2015) Narcolepsy in African Americans. Sleep 38:1673-81 |
Holm, Anja; Lin, Ling; Faraco, Juliette et al. (2015) EIF3G is associated with narcolepsy across ethnicities. Eur J Hum Genet 23:1573-80 |
Jacob, Louis; Leib, Ryan; Ollila, Hanna M et al. (2015) Comparison of Pandemrix and Arepanrix, two pH1N1 AS03-adjuvanted vaccines differentially associated with narcolepsy development. Brain Behav Immun 47:44-57 |
de Lecea, Luis (2015) Optogenetic control of hypocretin (orexin) neurons and arousal circuits. Curr Top Behav Neurosci 25:367-78 |
Showing the most recent 10 out of 55 publications