Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Specialized Center (P50)
Project #
5P50NS037409-09
Application #
7633137
Study Section
National Institute of Neurological Disorders and Stroke Initial Review Group (NSD)
Project Start
Project End
Budget Start
2008-06-01
Budget End
2009-05-31
Support Year
9
Fiscal Year
2008
Total Cost
$159,634
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Litvan, Irene; Lees, Peter S J; Cunningham, Christopher R et al. (2016) Environmental and occupational risk factors for progressive supranuclear palsy: Case-control study. Mov Disord 31:644-52
de Gusmão, Claudio M; Fuchs, Tania; Moses, Andrew et al. (2016) Dystonia-Causing Mutations as a Contribution to the Etiology of Spasmodic Dysphonia. Otolaryngol Head Neck Surg 155:624-8
Yokoi, Fumiaki; Chen, Huan-Xin; Dang, Mai Tu et al. (2015) Behavioral and electrophysiological characterization of Dyt1 heterozygous knockout mice. PLoS One 10:e0120916
Eskow Jaunarajs, K L; Bonsi, P; Chesselet, M F et al. (2015) Striatal cholinergic dysfunction as a unifying theme in the pathophysiology of dystonia. Prog Neurobiol 127-128:91-107
de Carvalho Aguiar, Patricia; Borges, Vanderci; Ferraz, Henrique Ballalai et al. (2015) Novel compound heterozygous mutations in PRKRA cause pure dystonia. Mov Disord 30:877-8
Nery, Flávia C; da Hora, Cintia C; Yaqub, Uzma et al. (2015) New methods for investigation of neuronal migration in embryonic brain explants. J Neurosci Methods 239:80-4
Yokoi, Fumiaki; Dang, Mai T; Liu, Jun et al. (2015) Decreased dopamine receptor 1 activity and impaired motor-skill transfer in Dyt1 ?GAG heterozygous knock-in mice. Behav Brain Res 279:202-10
Vaughn, Lauren S; Bragg, D Cristopher; Sharma, Nutan et al. (2015) Altered activation of protein kinase PKR and enhanced apoptosis in dystonia cells carrying a mutation in PKR activator protein PACT. J Biol Chem 290:22543-57
Nery, Flavia C; Atai, Nadia A; da Hora, Cintia C et al. (2014) Microfluidic platform to evaluate migration of cells from patients with DYT1 dystonia. J Neurosci Methods 232:181-188
Hettich, Jasmin; Ryan, Scott D; de Souza, Osmar Norberto et al. (2014) Biochemical and cellular analysis of human variants of the DYT1 dystonia protein, TorsinA/TOR1A. Hum Mutat 35:1101-13

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