The SPOTRIAS Network Sample Repository (SNSR) is a unique repository resource for the SPOTRIASnetwork, which proposes to collect, preserve, and make available unique biologic samples from patients withacute stroke. The specific goals of the SNSR include:1) Supervise and facilitate the collection, processing, and distributed storage of plasma samples frompatients with acute stroke. Through the well established clinical trials and community core infrastructurewithin each site in the SPOTRIAS network a large population of stroke patients will be available forrecruitment into the sample repository project. Plasma samples will be collected at several time intervalsand aliquots sent to the SPOTRIAS SNSR.2) Coordinate the collection of unique genetic samples from patients with acute stroke for contribution to theNINDS sponsored Coriell Cell Repository through the well established clinical trials and community coreinfrastructure within each site in the SPOTRIAS network a large population of stroke patients will beavailable for recruitment. Genetic materials collected through whole blood samples will be sent to the CoriellCell Repository and linked to the SNSR samples through the KAI database.3) Provide general oversight and management of the SNSR ensuring optimal storage of the plasmasamples to facilitate research by SPOTRIAS and NINDS investigators in stroke research. Utilizing bestpractices for repositories as defined by the International Society for Biological and EnvironmentalRepositories (ISBER) plasma samples will be available, upon approval of the SPOTRIAS SNSR SteeringCommittee, for use in stroke research.
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