Abstract

The Wisconsin National Primate Research Center (WNPRC) is one of seven federally supported National Primate Research Centers and the only one in the Midwest. WNPRC's mission is to increase the understanding of basic primate biology and to improve human health and quality of life through research. To accomplish this, the WNPRC helps discover treatments, preventions and cures for human disease; generates new knowledge of primate biology, from the molecular and whole animal levels to the understanding of primate ecosystems; facilitates research progress by providing expertise, resources and training to scientists worldwide; and collects primate information and disseminates to the research community and to the public.

Public Health Relevance

The Wisconsin National Primate Research Center (WNPRC) base operating grant supports services and resources for research addressing human health issues utilizing non-human primate (NHP) models. The WNPRC provides a rich and integrated portfolio of cutting-edge services, resources, and scientific expertise that support NHP research with high impact and direct relevance to human and animal health and disease. With ongoing additions to WNPRC infrastructure, and expansion of the Center's scientific components and collaborations, the WNPRC is poised to advance the translation of NHP research findings into new remedies for some of our society's most pressing medical problems.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
Primate Research Center Grants (P51)
Project #
5P51OD011106-58
Application #
9748648
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Hild, Sheri Ann
Project Start
1997-06-10
Project End
2022-04-30
Budget Start
2019-05-01
Budget End
2020-04-30
Support Year
58
Fiscal Year
2019
Total Cost
Indirect Cost

  Institution

Name
University of Wisconsin Madison
Department
Type
Graduate Schools
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715

  Publications

Slukvin, Igor I; Uenishi, Gene I (2018) Arterial identity of hemogenic endothelium: a key to unlock definitive hematopoietic commitment in hPSC cultures. Exp Hematol :
Macdonald, Jacob A; Corrado, Philip A; Nguyen, Sydney M et al. (2018) Uteroplacental and Fetal 4D Flow MRI in the Pregnant Rhesus Macaque. J Magn Reson Imaging :
Schmidt, Jenna Kropp; Block, Lindsey N; Golos, Thaddeus G (2018) Defining the rhesus macaque placental miRNAome: Conservation of expression of placental miRNA clusters between the macaque and human. Placenta 65:55-64
Aliota, Matthew T; Dudley, Dawn M; Newman, Christina M et al. (2018) Molecularly barcoded Zika virus libraries to probe in vivo evolutionary dynamics. PLoS Pathog 14:e1006964
Reyes, Leticia; Phillips, Priscilla; Wolfe, Bryce et al. (2018) Porphyromonas gingivalis and adverse pregnancy outcome. J Oral Microbiol 10:1374153
Ellis-Connell, Amy L; Balgeman, Alexis J; Zarbock, Katie R et al. (2018) ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in the Absence of Antiretroviral Treatment. J Virol 92:
Martins, Mauricio A; Tully, Damien C; Pedreño-Lopez, Núria et al. (2018) Mamu-B*17+ Rhesus Macaques Vaccinated with env, vif, and nef Manifest Early Control of SIVmac239 Replication. J Virol 92:
Abbott, David H; Vepraskas, Sarah H; Horton, Teresa H et al. (2018) Accelerated Episodic Luteinizing Hormone Release Accompanies Blunted Progesterone Regulation in PCOS-like Female Rhesus Monkeys (Macaca Mulatta) Exposed to Testosterone during Early-to-Mid Gestation. Neuroendocrinology 107:133-146
Dudley, Dawn M; Van Rompay, Koen K; Coffey, Lark L et al. (2018) Miscarriage and stillbirth following maternal Zika virus infection in nonhuman primates. Nat Med 24:1104-1107
Seth, Nitin; Simmons, Heather A; Masood, Farah et al. (2018) Model of Traumatic Spinal Cord Injury for Evaluating Pharmacologic Treatments in Cynomolgus Macaques (Macaca fasicularis). Comp Med 68:63-73

Showing the most recent 10 out of 334 publications