Abstract

The California National Primate Research Center (CNPRC) Is one of eight National Primate Research Centers (NPRCs) funded by the National Institutes of Health, National Center for Research Resource. This renewal application seeksisupport for Administrative Services, Primate Services, Core Science Services, Research Units and Modernization and Improvement. To enhance the CNPRC's ability to serve as a regional, national, and international resource and provide the infrastructure support essential to conduct successful research on nonhuman primates, we are proposing the following specific aims. 1) Advance translational research through the development of nonhuman primate models; 2) Foster an environment that encourages and emphasizes the scientific expertise that is critical to carry out the mission of the NPRC Program and the CNPRC; 3) Encourage partnerships to maximize the research investment; 4) Enhance the research infrastructure; 5) Strengthen the research workforce; 6) Increase efficiencies in the use of CNPRC resources.

Public Health Relevance

The CNPRC will expand collaborations to enhance translational research through the development of new nonhuman primate models of disease by utilizing basic knowledge and technologies of Staff Scientists and scientists outside of the CNPRC.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Office of The Director, National Institutes of Health (OD)
Type
Primate Research Center Grants (P51)
Project #
3P51OD011107-53S2
Application #
8899678
Study Section
Special Emphasis Panel (ZRR1-CM-5 (01))
Program Officer
Harding, John D
Project Start
1997-05-01
Project End
2015-04-30
Budget Start
2014-08-21
Budget End
2015-04-30
Support Year
53
Fiscal Year
2014
Total Cost
$499,950
Indirect Cost

  Institution

Name
University of California Davis
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618

  Publications

Brock, J H; Rosenzweig, E S; Yang, H et al. (2018) Enhanced axonal transport: A novel form of ""plasticity"" after primate and rodent spinal cord injury. Exp Neurol 301:59-69
Yiu, Glenn; Wang, Zhe; Munevar, Christian et al. (2018) Comparison of chorioretinal layers in rhesus macaques using spectral-domain optical coherence tomography and high-resolution histological sections. Exp Eye Res 168:69-76
Baxter, Mark G; Santistevan, Anthony C; Bliss-Moreau, Eliza et al. (2018) Timing of cyclic estradiol treatment differentially affects cognition in aged female rhesus monkeys. Behav Neurosci 132:213-223
Phillips, Bonnie; Van Rompay, Koen K A; Rodriguez-Nieves, Jennifer et al. (2018) Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques. J Virol 92:
Ruebel, Meghan L; Schall, Peter Z; Midic, Uros et al. (2018) Transcriptome analysis of rhesus monkey failed-to-mature oocytes: deficiencies in transcriptional regulation and cytoplasmic maturation of the oocyte mRNA population. Mol Hum Reprod 24:478-494
Smit-McBride, Zeljka; Nguyen, Johnny; Elliott, Garrett W et al. (2018) Effects of aging and environmental tobacco smoke exposure on ocular and plasma circulatory microRNAs in the Rhesus macaque. Mol Vis 24:633-646
Flaherman, Valerie J; Narayan, Nicole R; Hartigan-O'Connor, Dennis et al. (2018) The Effect of Early Limited Formula on Breastfeeding, Readmission, and Intestinal Microbiota: A Randomized Clinical Trial. J Pediatr 196:84-90.e1
Schmidt, Brian A; Phillips, Ronald; Rolston, Matthew et al. (2018) Comparison of sampling methods for profiling cervicovaginal microbiome in rhesus macaques. J Med Primatol :
Cherry, Simon R; Jones, Terry; Karp, Joel S et al. (2018) Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care. J Nucl Med 59:3-12
Lemoy, Marie-Josee Mf; Salyards, Gregory W; Keesler, Rebekah I et al. (2018) Primary Myxoid Liposarcoma of the Greater Omentum in a Rhesus Macaque (Macaca mulatta). Comp Med 68:308-313

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