This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: The Center for Fetal Monkey Gene Transfer has the dual function of conducting research on crucial questions in cell and gene-based therapies in nonhuman primates and providing extensive outreach to NHLBI-funded investigators. The mission of the Gene Therapy Center is three-fold: (1) to use established monkey models to explore fetal approaches for heart, lung, and blood diseases; (2) to evaluate the safety and efficiency of cell and gene-based strategies for potential human application; and (3) to provide NHLBI-funded investigators with essential expertise and resources through an annual call for proposals. In addition to extensive outreach, the Gene Therapy Center provides training to investigators and their staff, and develops new techniques and methodologies each year that are shared with the greater research communit
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