TheInformationDisseminationCoreofTheScrippsResearchInstituteAlcoholResearchCenter(TSRI-ARC) willdisseminatescientificresearchfindingsmadebyARClabstothepublicthrougheducationalandoutreach efforts and will particularly target NIAAA-identified ?Special Populations? (youth under age 21, college-age young adults, senior citizens, women, and ethnic and racial minorities) that have characteristics that make themmoresusceptibletothenegativeconsequencesofalcoholuse.Importantly,thesepopulationsalsoareat high risk for stress, the primary focus of TSRI-ARC.
Core Specific Aims are the 1) Development of curricula targeted to high-risk populations, 2) Expansion of internships targeted to high-risk populations, and 3) Outreachthroughenhancedsocialmediaandparenteducation.Thegoalsoftheseaimsaretototeachhigh- riskpopulationsandthosewhointeractwiththemhowthebrainisaffectedbyalcohol,theprogressionofthese effectswithcontinueduse,andtheconceptofthe?darkside?ofaddictionusingspecificexamplesfromTSRI- ARC laboratories, to directly interact with the community through laboratory tours and a continuation and expansionofourinternshipprogram,andtomaketheTSRI-ARCwebsitemoreaccessibletothepublicandto use it for communication between TSRI-ARC PIs as well as a critical resource for each of our curriculum efforts.

National Institute of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Comprehensive Center (P60)
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Special Emphasis Panel (ZAA1)
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Scripps Research Institute
La Jolla
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Schmeichel, Brooke E; Matzeu, Alessandra; Koebel, Pascale et al. (2018) Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats. Neuropsychopharmacology 43:2373-2382
Kononoff, Jenni; Kallupi, Marsida; Kimbrough, Adam et al. (2018) Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats. eNeuro 5:
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