UCLA proposes to establish an OAIC that comprehensively addresses independence issues in subjects ranging from the well to the institutionalized elderly. In all cases, intervention studies are based on existing research projects with proven track records and will be performed by nationally recognized teams. Initially, there are three intervention and two intervention development studies; later, two added intervention studies are planned. All of these except one of the intervention development studies target people at high risk for independence loss. One study addresses an exercise trial coupled with a motivational program in fall-prone elderly, and one deals with health-related decision-making skills of elders. The three geriatric assessment interventions focus on community-dwelling elders with multiple risk factors for decline, hospitalized elders who are medically unstable, and patients who are designated as """"""""short-stayers"""""""" in nursing homes. Common to all three geriatric assessment studies are efforts to prevent institutionalization and trials of procedures designed to improve the probability that assessment recommendations are implemented. Subjects of the last intervention are nursing home residents whose problems are exacerbated by nursing care that reinforces dependency due to incontinence and restraint management. All projects are linked by common efforts to motivate target subjects to implement and maintain independence-enhancing interventions. Thus, the major theme of the proposed UCLA Center is to translate effective intervention procedures into the daily practices of patients and care- providers. Evaluation and administrative procedures that will guide the evolution of Pilot and Intervention Development Projects into major interventions have been articulated within the Administrative and Research Development Cores. A Research Development Core uses the major intervention studies as settings for enriching the training of junior faculty. In addition, pilot projects are planned that relate to each intervention program. Mentorship programs based on the extensive professional resources within the system are designed both to support the major research projects and develop the geriatric research skills of an interdisciplinary group of junior faculty. The Research Resources Core will provide support to all projects by assisting with measurement methods and techniques for assessing cost and effectiveness. A core for Dissemination of Information is also planned.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Comprehensive Center (P60)
Project #
5P60AG010415-05
Application #
2051655
Study Section
Biological and Clinical Aging Review Committee (BCA)
Project Start
1991-09-30
Project End
1996-06-30
Budget Start
1995-11-10
Budget End
1996-06-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Herbst, Allen; Widjaja, Kevin; Nguy, Beatrice et al. (2017) Digital PCR Quantitation of Muscle Mitochondrial DNA: Age, Fiber Type, and Mutation-Induced Changes. J Gerontol A Biol Sci Med Sci 72:1327-1333
Rodriguez, Juan C; Dzierzewski, Joseph M; Fung, Constance H et al. (2015) Association Between Pain and Functional Independence in Older Adults During and After Admission to Rehabilitation After an Acute Illness or Injury. J Am Geriatr Soc 63:2275-81
Dzierzewski, Joseph M; Mitchell, Michael; Rodriguez, Juan Carlos et al. (2015) Patterns and predictors of sleep quality before, during, and after hospitalization in older adults. J Clin Sleep Med 11:45-51
Sacco, Paul; Unick, George Jay; Kuerbis, Alexis et al. (2015) Alcohol-Related Diagnoses in Hospital Admissions for All Causes Among Middle-Aged and Older Adults: Trends and Cohort Differences From 1993 to 2010. J Aging Health 27:1358-74
Kuerbis, Alexis N; Yuan, Stanley E; Borok, Jenna et al. (2015) Testing the initial efficacy of a mailed screening and brief feedback intervention to reduce at-risk drinking in middle-aged and older adults: the comorbidity alcohol risk evaluation study. J Am Geriatr Soc 63:321-6
Sanna, Maija B; Tuqan, Alia T; Goldsmith, Jeff S et al. (2015) Characteristics of older at-risk drinkers who drive after drinking and those who do not drive after drinking. Traffic Inj Prev 16:104-8
Martin, Jennifer L; Dzierzewski, Joseph M; Mitchell, Michael et al. (2013) Patterns of sleep quality during and after postacute rehabilitation in older adults: a latent class analysis approach. J Sleep Res 22:640-7
Silver, H J; Wall, R; Hollingsworth, E et al. (2013) Simple kcal/kg formula is comparable to prediction equations for estimating resting energy expenditure in older cognitively impaired long term care residents. J Nutr Health Aging 17:39-44
Borok, Jenna; Galier, Peter; Dinolfo, Matteo et al. (2013) Why do older unhealthy drinkers decide to make changes or not in their alcohol consumption? Data from the Healthy Living as You Age study. J Am Geriatr Soc 61:1296-302
Kierlin, Lara; Olmstead, Richard; Yokomizo, Megumi et al. (2012) Diagnostic and Statistical Manual criteria for insomnia related impairment in daytime functioning: polysomnographic correlates in older adults. Sleep Med 13:958-60

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