The Research and Development Core seeks to promote and augment institutional involvement in geriatric based research and to specifically focus on aging associated disability. These efforts will be in part accomplished by supporting promising junior faculty and by funding high quality pilot research projects. The Research and Development Core will specifically promote mechanistic and outcome based research activities. In addition, the integration of mechanistic and outcome-based research will be facilitated by working closely with members of other cores and projects to: 1) seek potential new areas of collaboration; 2) encourage efforts which link mechanism and outcome research; 3) prioritize pilot study funding to optimize our integration of mechanistic and outcome studies and 4) continue to encourage new collaborative efforts by content area experts to facilitate their involvement in a geriatric-based research program. Detailed training plans are created for each junior faculty member supported by the core. These training plans are tailored to meet individual needs and generally involve didactic training, funding of pilot research projects, provision of support for travel to scientific meetings and providing access to nationally known experts both within and outside the institution. The leadership of the core monitors the scientific progress of each junior faculty person through a formal evaluation process held every 6 months. In addition to this formal process an informal update is conducted at the bi-weekly meetings of the Pepper Center group. Specific decisions pertaining to funding pilot projects and supporting junior faculty will be made in a matter consistent with the major themes of the Pepper Center. Specific criteria include: 1) augmenting the basic science research and training program, 2) the development of health services research training program and 3) the maintenance and expansion of the existing focus in clinical trials and epidemiology. The Research and Development Core works closely with other resources at Bowman Gray School of Medicine including: the J. Paul Sticht Center on Aging; the NIA funded post-doctoral training program; and the large number of pertinent research efforts within the institution. These efforts by the Research and Development Core will facilitate a continued high level of excellence of geriatric and disability related research efforts.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Comprehensive Center (P60)
Project #
3P60AG010484-10S1
Application #
6487724
Study Section
Project Start
2001-08-15
Project End
2002-09-30
Budget Start
Budget End
Support Year
10
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Type
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Li, Yanhong; Levy, Wayne C; Neilson, Matthew P et al. (2014) Associations between seattle heart failure model scores and medical resource use and costs: findings from HF-ACTION. J Card Fail 20:541-7
Li, Yanhong; Neilson, Matthew P; Whellan, David J et al. (2013) Associations between Seattle Heart Failure Model scores and health utilities: findings from HF-ACTION. J Card Fail 19:311-6
Flynn, Kathryn E; Lin, Li; Moe, Gordon W et al. (2012) Relationships between changes in patient-reported health status and functional capacity in outpatients with heart failure. Am Heart J 163:88-94.e3
Swank, Ann M; Horton, John; Fleg, Jerome L et al. (2012) Modest increase in peak VO2 is related to better clinical outcomes in chronic heart failure patients: results from heart failure and a controlled trial to investigate outcomes of exercise training. Circ Heart Fail 5:579-85
Miller, G D; Nicklas, B J; Davis, C C et al. (2012) Basal growth hormone concentration increased following a weight loss focused dietary intervention in older overweight and obese women. J Nutr Health Aging 16:169-74
Reed, Shelby D; Li, Yanhong; Dunlap, Mark E et al. (2012) In-hospital resource use and medical costs in the last year of life by mode of death (from the HF-ACTION randomized controlled trial). Am J Cardiol 110:1150-5
Reed, Shelby D; Li, Yanhong; Ellis, Stephen J et al. (2012) Associations between hemoglobin level, resource use, and medical costs in patients with heart failure: findings from HF-ACTION. J Card Fail 18:784-91
Messier, S P; Legault, C; Loeser, R F et al. (2011) Does high weight loss in older adults with knee osteoarthritis affect bone-on-bone joint loads and muscle forces during walking? Osteoarthritis Cartilage 19:272-80
Arena, Ross; Myers, Jonathan; Abella, Joshua et al. (2011) Cardiopulmonary exercise testing is equally prognostic in young, middle-aged and older individuals diagnosed with heart failure. Int J Cardiol 151:278-83
Morris, Peter E; Griffin, Leah; Berry, Michael et al. (2011) Receiving early mobility during an intensive care unit admission is a predictor of improved outcomes in acute respiratory failure. Am J Med Sci 341:373-7

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