Abstract

. The Biostatistics Core (RRC-E) will serve as a resource and collaborator for the intervention studies, IS-1 and IS-2, the pilot projects, and the other RRCs. The Core leader will provide ongoing advice and recommendations regarding the statistical, sample size, and data quality implications of protocol design issues and of proposed protocol modifications. This Core will have overall responsibility for designing data entry systems, for building quality control measures into those systems, and for all data analyses. The RRC-E will: 1) collaborate with investigators on the experimental design of all projects and the design of all questionnaires and forms; 2) oversee the development and implementation of efficient and high quality data entry/management procedures for all RRCs and research projects; 3) work with investigators on an ongoing basis to ensure that the requirements of each protocol are being satisfied; and 4) oversee the statistical analysis and interpretation of all data and work with investigators in preparing publications reporting the results of the research of the OAIC. The RRC-E will also serve as a resource to new investigators in the RDC interested in gaining competence in the design and statistical analysis of intervention studies.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Comprehensive Center (P60)
Project #
5P60AG013629-05
Application #
6201059
Study Section
Project Start
1999-09-01
Project End
2000-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
5
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Schneider, Joanne Kraenzle (2009) Refinement and validation of the episode-specific interpretations of exercise inventory. J Nurs Meas 17:148-63
Evans, Ellen M; Racette, Susan B; Van Pelt, Rachael E et al. (2007) Effects of soy protein isolate and moderate exercise on bone turnover and bone mineral density in postmenopausal women. Menopause 14:481-8
Weiss, Edward P; Spina, Robert J; Holloszy, John O et al. (2006) Gender differences in the decline in aerobic capacity and its physiological determinants during the later decades of life. J Appl Physiol 101:938-44
Carr, David B; Flood, Kelliel; Steger-May, Karen et al. (2006) Characteristics of frail older adult drivers. J Am Geriatr Soc 54:1125-9
Racette, Susan B; Evans, Ellen M; Weiss, Edward P et al. (2006) Abdominal adiposity is a stronger predictor of insulin resistance than fitness among 50-95 year olds. Diabetes Care 29:673-8
Villareal, Dennis T; Holloszy, John O (2006) DHEA enhances effects of weight training on muscle mass and strength in elderly women and men. Am J Physiol Endocrinol Metab 291:E1003-8
Evans, Ellen M; Racette, Susan B; Peterson, Linda R et al. (2005) Aerobic power and insulin action improve in response to endurance exercise training in healthy 77-87 yr olds. J Appl Physiol 98:40-5
Villareal, Dennis T; Steger-May, K; Schechtman, K B et al. (2004) Effects of exercise training on bone mineral density in frail older women and men: a randomised controlled trial. Age Ageing 33:309-12
Schneider, Joanne Kraenzle; Mercer, Gina Touch; Herning, Margaret et al. (2004) Promoting exercise behavior in older adults: using a cognitive behavioral intervention. J Gerontol Nurs 30:45-53
Villareal, Dennis T; Holloszy, John O (2004) Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial. JAMA 292:2243-8

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