Core - Biostatistical and Epidemiology Services

Clive, Jonathan M.

Abstract

This OAIC unit is not a Research Resources Core; Biostatistical and Epidemiologic Services will be provided to the UCHC OAIC by the Epidemiology and Biostatistical Core of the UCHC NIH-funded General Clinical Research Center (GCRC). These services will be provided half by charges to OAIC and half donated by the GCRC, and are designated Biostat/epi for OAIC.
Specific aims i nclude providing 1) Biostat/epi Services for investigators on OAIC projects (IDSs, Pilots, future ISs); 2) Biostat/epi education and services to RDC trainees' and 3) initial Biostat/epi services to investigators on external projects using OAIC RRCs, and to investigators starting independence-related research projects regardless of funding. Jonathan Clive, PhD, Director of the UCHC Office of Biostatistical Consultation (OBC), and GCRC epi/Biostat Core Director, will manage all OAIC Biostat/epi Services. He will both provide services directly and enlist other OBC faculty to assist him. The recent award of a GCRC supplement grant ($530,000, 4 years) for a Computerized Data Management and Analysis System (CDMAS) to meet all data entry, storage, management and analysis needs for the GCRC and its many investigators will be leveraged on behalf of the OAIC. One work station will be installed in the space of the Balance and Gait Enhancement Laboratory and the Exercise Lab-Osteoporosis Center and connected to the CDMAS. OAIC will have unlimited use of CDMAS hardware, software and staff for the low price of the work station.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Aging (NIA)
• Type: Comprehensive Center (P60)
• Project #: 1P60AG013631-01
• Application #: 5205050
• Support Year: 1
• Fiscal Year: 1996

Publications

Fragala, Maren S; Dam, Thuy-Tien L; Barber, Vanessa et al. (2015) Strength and function response to clinical interventions of older women categorized by weakness and low lean mass using classifications from the Foundation for the National Institute of Health sarcopenia project. J Gerontol A Biol Sci Med Sci 70:202-9

Fragala, Maren S; Clark, M H; Walsh, Stephen J et al. (2012) Gender differences in anthropometric predictors of physical performance in older adults. Gend Med 9:445-56

Kenny, Anne M; Kleppinger, Alison; Annis, Kristen et al. (2010) Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels, low bone mass, and physical frailty. J Am Geriatr Soc 58:1134-43

Estrada, Marcos; Kleppinger, Alison; Judge, James O et al. (2007) Functional impact of relative versus absolute sarcopenia in healthy older women. J Am Geriatr Soc 55:1712-9

Pefanco, Mary Ann; Kenny, Anne M; Kaplan, Richard F et al. (2007) The effect of 3-year treatment with 0.25 mg/day of micronized 17beta-estradiol on cognitive function in older postmenopausal women. J Am Geriatr Soc 55:426-31

Kenny, Anne M; Waynik, Ilana Y; Smith, JoAnne et al. (2006) Association between level of frailty and bone mineral density in community-dwelling men. J Clin Densitom 9:309-14

Unson, Christine G; Fortinsky, Richard; Prestwood, Karen et al. (2005) Osteoporosis medications used by older African-American women: effects of socioeconomic status and psychosocial factors. J Community Health 30:281-97

Boxer, R S; Kenny, A M; Dowsett, R et al. (2005) The effect of 6 months of androgen deprivation therapy on muscle and fat mass in older men with localized prostate cancer. Aging Male 8:207-12

Judge, James Oat; Kleppinger, Alison; Kenny, Anne et al. (2005) Home-based resistance training improves femoral bone mineral density in women on hormone therapy. Osteoporos Int 16:1096-108

Kenny, Anne M; Kleppinger, Alison; Wang, Yahzen et al. (2005) Effects of ultra-low-dose estrogen therapy on muscle and physical function in older women. J Am Geriatr Soc 53:1973-7