The Outcomes Measurement Core, (RRC-B) will identify, develop, and support the collection of outcome measures in the proposed Intervention Development Studies and in affiliated external, NIH funded research projects. The Outcomes Measurement Core will enhance research quality by integrating a multidimensional approach to outcomes assessment across studies and will augment efficiency by having a central facility and administration for coordinating outcome assessment. By taking a multidisciplinary approach, the Outcomes Measurement Core will enable investigators to assess both the direct (the value of patient services) and indirect (value of quality of life impacts) costs incurred, or avoided, through the interventions proposed in the Intervention Developmental Studies and the external studies. Having the RRC-B optimizes the interaction of basic and behavioral scientists in evaluating outcomes, which is critically important in maintaining independence in older Americans. Finally, the RRC-B has considerable potential for fostering growth in outcomes assessment in aging research, as the Lowell P. Weicker General Clinical Research Center, the UConn Multipurpose Arthritis and Musculoskeletal Diseases Center, and the Travelers Center on Aging continue to expand and to develop new clinical research projects. Outcome measures are organized into seven domains, each with an identified expert manager. They are: 1) measured function 2) reported function; 3) osteoarthritis assessment; 4) service use and caregiver burden; 5) economic impact; 6) behavioral/cognitive outcomes; and 7) biomedical markers of bone. The cognitive/behavioral domain also includes responsibility for overseeing and enhancing adherence with therapeutic regimens and health promotion behaviors. The expert managers and the director will meet quarterly and as needed to review ongoing research in OAIC and external projects, collection of outcome measures, proposed research projects, and projects under development. The OMC management team, in consultation with the OAIC PIs will select and set priorities among affiliated projects to receive outcomes core support using the following criteria: relevance and responsiveness to the UCHC OAIC goals, relationship to ongoing research foci (e.g., opportunities to supplement or leverage), and quality of research- demonstration design. Quality assurance for outcomes measures will be monitored closely by working with each of the PIs and expert-managers.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Comprehensive Center (P60)
Project #
5P60AG013631-05
Application #
6398538
Study Section
Project Start
2000-09-01
Project End
2003-08-31
Budget Start
Budget End
Support Year
5
Fiscal Year
2000
Total Cost
Indirect Cost
Name
University of Connecticut
Department
Type
DUNS #
City
Farmington
State
CT
Country
United States
Zip Code
06030
Fragala, Maren S; Dam, Thuy-Tien L; Barber, Vanessa et al. (2015) Strength and function response to clinical interventions of older women categorized by weakness and low lean mass using classifications from the Foundation for the National Institute of Health sarcopenia project. J Gerontol A Biol Sci Med Sci 70:202-9
Fragala, Maren S; Clark, M H; Walsh, Stephen J et al. (2012) Gender differences in anthropometric predictors of physical performance in older adults. Gend Med 9:445-56
Kenny, Anne M; Kleppinger, Alison; Annis, Kristen et al. (2010) Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels, low bone mass, and physical frailty. J Am Geriatr Soc 58:1134-43
Estrada, Marcos; Kleppinger, Alison; Judge, James O et al. (2007) Functional impact of relative versus absolute sarcopenia in healthy older women. J Am Geriatr Soc 55:1712-9
Pefanco, Mary Ann; Kenny, Anne M; Kaplan, Richard F et al. (2007) The effect of 3-year treatment with 0.25 mg/day of micronized 17beta-estradiol on cognitive function in older postmenopausal women. J Am Geriatr Soc 55:426-31
Kenny, Anne M; Waynik, Ilana Y; Smith, JoAnne et al. (2006) Association between level of frailty and bone mineral density in community-dwelling men. J Clin Densitom 9:309-14
Unson, Christine G; Fortinsky, Richard; Prestwood, Karen et al. (2005) Osteoporosis medications used by older African-American women: effects of socioeconomic status and psychosocial factors. J Community Health 30:281-97
Boxer, R S; Kenny, A M; Dowsett, R et al. (2005) The effect of 6 months of androgen deprivation therapy on muscle and fat mass in older men with localized prostate cancer. Aging Male 8:207-12
Judge, James Oat; Kleppinger, Alison; Kenny, Anne et al. (2005) Home-based resistance training improves femoral bone mineral density in women on hormone therapy. Osteoporos Int 16:1096-108
Kenny, Anne M; Kleppinger, Alison; Wang, Yahzen et al. (2005) Effects of ultra-low-dose estrogen therapy on muscle and physical function in older women. J Am Geriatr Soc 53:1973-7

Showing the most recent 10 out of 50 publications