Abstract

To perform a randomized controlled trial to assess the effectiveness and cost-effectiveness of lumbar fusion and use of instrumentation in the surgical management of patients with degenerative lumbar spinal stenosis.
Specific aims of Development and Feasibility Study: (1) Design multicenter randomized controlled trial; in particular, establish consensus among surgeon co-investigators on criteria for randomization to fusion and to instrumentation; (2) Collect pilot data to document the feasibility of a multicenter randomized controlled study of spinal fusion and examine preliminary results.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Comprehensive Center (P60)
Project #
5P60AR036308-12
Application #
5206180
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Koch-Weser, Susan; Rudd, Rima E; Dejong, William (2010) Quantifying word use to study health literacy in doctor-patient communication. J Health Commun 15:590-602
Simard, Julia F; Karlson, Elizabeth W; Costenbader, Karen H et al. (2008) Perinatal factors and adult-onset lupus. Arthritis Rheum 59:1155-61
Costenbader, Karen H; Feskanich, Diane; Mandl, Lisa A et al. (2006) Smoking intensity, duration, and cessation, and the risk of rheumatoid arthritis in women. Am J Med 119:503.e1-9
Karlson, E W; Costenbader, K H; McAlindon, T E et al. (2005) High sensitivity, specificity and predictive value of the Connective Tissue Disease Screening Questionnaire among urban African-American women. Lupus 14:832-6
Katz, Jeffrey N; Amick 3rd, Benjamin C; Keller, Robert et al. (2005) Determinants of work absence following surgery for carpal tunnel syndrome. Am J Ind Med 47:120-30
Punnett, L; Gold, J; Katz, J N et al. (2004) Ergonomic stressors and upper extremity musculoskeletal disorders in automobile manufacturing: a one year follow up study. Occup Environ Med 61:668-74
Costenbader, Karen H; Wright, Elizabeth; Liang, Matthew H et al. (2004) Cardiac risk factor awareness and management in patients with systemic lupus erythematosus. Arthritis Rheum 51:983-8
Iversen, Maura D; Eaton, Holley M; Daltroy, Lawren H (2004) How rheumatologists and patients with rheumatoid arthritis discuss exercise and the influence of discussions on exercise prescriptions. Arthritis Rheum 51:63-72
Costenbader, Karen H; Kim, Daniel J; Peerzada, Jehanna et al. (2004) Cigarette smoking and the risk of systemic lupus erythematosus: a meta-analysis. Arthritis Rheum 50:849-57
Karlson, Elizabeth W; Liang, Matthew H; Eaton, Holley et al. (2004) A randomized clinical trial of a psychoeducational intervention to improve outcomes in systemic lupus erythematosus. Arthritis Rheum 50:1832-41

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