The established mission of the Methodology Core for the UAB Multidisciplinary Clinical Research Center (MCRC) is to develop and provide state of the art methodology and methodological education in the collaborative support of clinical and translational research in arthritis and musculoskeletal disease (MSD) at the local, regional, national, and international level. Toward this goal, the Methodology Core will continue to provide the statistical, epidemiological, outcomes research, statistical genetics, economics/cost effectiveness, and bioinformatics leadership and expertise required to develop and perform cutting-edge clinical research in arthritis and MSD as it pursues four broad goals are to: I. Support the design, data collection, management, and analytic efforts of the MCRC projects. II. Nurture original research in methodology applicable to clinical research in arthritis and MSD. III. Develop new investigators in the area of arthritis and MSD research. IV. Provide methodology seminars, workshops, and mini-courses to introduce the newest methodological approaches to the MCRC research base.

Public Health Relevance

of this core is defined by the core's mission to assist in the design, data collection, analysis and general oversight of the proposed projects, to develop new research projects from within the research base, and provide educational opportinities to the members of the research base.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Comprehensive Center (P60)
Project #
5P60AR064172-02
Application #
8735068
Study Section
Special Emphasis Panel (ZAR1-KM)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
2
Fiscal Year
2014
Total Cost
$259,321
Indirect Cost
$85,433
Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Hartman, Holly; Wang, Yuge; Schroeder Jr, Harry W et al. (2018) Absorbance summation: A novel approach for analyzing high-throughput ELISA data in the absence of a standard. PLoS One 13:e0198528
Stoll, Matthew L; Pierce, M Kathy; Watkins, Jordan A et al. (2018) Akkermansia muciniphila is permissive to arthritis in the K/BxN mouse model of arthritis. Genes Immun :
Curtis, Jeffrey R; Chen, Lang; Danila, Maria I et al. (2018) Routine Use of Quantitative Disease Activity Measurements among US Rheumatologists: Implications for Treat-to-target Management Strategies in Rheumatoid Arthritis. J Rheumatol 45:40-44
Stoll, Matthew L; Weiss, Pamela F; Weiss, Jennifer E et al. (2018) Age and fecal microbial strain-specific differences in patients with spondyloarthritis. Arthritis Res Ther 20:14
Curtis, Jeffrey R; Chen, Lang; Higginbotham, Phillip et al. (2017) Social media for arthritis-related comparative effectiveness and safety research and the impact of direct-to-consumer advertising. Arthritis Res Ther 19:48
Yun, Huifeng; Xie, Fenglong; Beyl, Randall N et al. (2017) Risk of Hypersensitivity to Biologic Agents Among Medicare Patients With Rheumatoid Arthritis. Arthritis Care Res (Hoboken) 69:1526-1534
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Curtis, Jeffrey R; Chen, Lang; Greenberg, Jeffrey D et al. (2017) The clinical status and economic savings associated with remission among patients with rheumatoid arthritis: leveraging linked registry and claims data for synergistic insights. Pharmacoepidemiol Drug Saf 26:310-319
Yen, Po-Yin; Lara, Barbara; Lopetegui, Marcelo et al. (2016) Usability and Workflow Evaluation of ""RhEumAtic Disease activitY"" (READY). A Mobile Application for Rheumatology Patients and Providers. Appl Clin Inform 7:1007-1024
Stoll, Matthew L; Cron, Randy Q (2016) The microbiota in pediatric rheumatic disease: epiphenomenon or therapeutic target? Curr Opin Rheumatol 28:537-43

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