The goal of the training program within the Center for Hearing Loss in children is to develop additional independent investigators and clinical professionals with the knowledge and skills required to address the critical issues associated with childhood hearing loss. To provide opportunities for physicians, postdoctoral fellows, predoctoral fellows, and members of underrepresented minorities to take advantage of the environment and resources of the Center, we propose a five-part program. First, an M.D.-Ph.D. program will provide training for careers in academic medicine; this program replaces a one-year training program that was part of the current grant cycle. Second, a Postdoctoral Fellowship program will provide two fellowship positions in addition to the three available through our Institutional Postdoctoral Training Grant. Third, a Predoctoral Fellowship program will provide four positions for well- qualified graduate students to work in our laboratories. Fourth, a Graduate Fellowship program for members of underrepresented racial/ethnic minorities will provide laboratory experience for students who have received undergraduate degrees but want additional training before entering graduate school. Fifth, a Summer Science Intern Program for deaf and minority undergraduates will provide laboratory experience and information about careers in science that may not have been available at the interns' home universities.

Project Start
1998-09-01
Project End
1999-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
9
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Father Flanagan's Boys' Home
Department
Type
DUNS #
City
Boys Town
State
NE
Country
United States
Zip Code
68010
Song, Lei; McGee, Joann; Walsh, Edward J (2008) The influence of thyroid hormone deficiency on the development of cochlear nonlinearities. J Assoc Res Otolaryngol 9:464-76
Song, Lei; McGee, JoAnn; Walsh, Edward J (2008) Development of cochlear amplification, frequency tuning, and two-tone suppression in the mouse. J Neurophysiol 99:344-55
Varga, R; Avenarius, M R; Kelley, P M et al. (2006) OTOF mutations revealed by genetic analysis of hearing loss families including a potential temperature sensitive auditory neuropathy allele. J Med Genet 43:576-81
Song, Lei; McGee, Jo Ann; Walsh, Edward J (2006) Consequences of combined maternal, fetal and persistent postnatal hypothyroidism on the development of auditory function in Tshrhyt mutant mice. Brain Res 1101:59-72
Song, Lei; McGee, Joann; Walsh, Edward J (2006) Frequency- and level-dependent changes in auditory brainstem responses (ABRS) in developing mice. J Acoust Soc Am 119:2242-57
Higgins, Maureen B; McCleary, Elizabeth A; Ide-Helvie, Dana L et al. (2005) Speech and voice physiology of children who are hard of hearing. Ear Hear 26:546-58
Pennings, Ronald J E; Topsakal, Vedat; Astuto, Lisa et al. (2004) Variable clinical features in patients with CDH23 mutations (USH1D-DFNB12). Otol Neurotol 25:699-706
Varga, R; Kelley, P M; Keats, B J et al. (2003) Non-syndromic recessive auditory neuropathy is the result of mutations in the otoferlin (OTOF) gene. J Med Genet 40:45-50
Higgins, Maureen B; McCleary, Elizabeth A; Carney, Arlene Earley et al. (2003) Longitudinal changes in children's speech and voice physiology after cochlear implantation. Ear Hear 24:48-70
Bhattacharya, Gautam; Miller, Caroline; Kimberling, William J et al. (2002) Localization and expression of usherin: a novel basement membrane protein defective in people with Usher's syndrome type IIa. Hear Res 163:1-11

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