The Comprehensive Oral Health Research Center of Discovery (COHRCD) involves projects ranging from pre-clinical studies to translational studies, clinical and behavioral intervention trials, effectiveness research, and health services research. The Biostatistical and Research Design (BARD) Core will tailor support for each study, since each project has specific research design and statistical analysis needs. The BARD Core will provide advice, education, and statistical consulting to all COHRCD projects and investigators. The BARD Core will continue to work with investigators to refine protocols and data collection instruments, will finalize plans for randomization schedules, data management, monitoring, quality control and reliability; coordinate integrating databases from different projects to enable more powerful, unique multivariate analyses; provide statistical consulting for baseline, interim, and final analyses; educate researchers about selecting statistical methods for their research design and analyses and about interpreting the results; foster developing a more comprehensive electronic patient record database in the UCSF School of Dentistry clinics; and promote the development of quality research studies based on pilot projects, on intermediate results on major studies, and on related endeavors from residents, graduate students, postdoctoral fellows, and faculty via the Clinical Research Center without Walls. Sufficient time and effort should be given to the data analytic aspects of research, as with any other step in the research process. The doctoral level BARD Core personnel have over 70 person-years of collaborative research experience and can adequately fulfill those needs.

National Institute of Health (NIH)
National Institute of Dental & Craniofacial Research (NIDCR)
Comprehensive Center (P60)
Project #
Application #
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California San Francisco
San Francisco
United States
Zip Code
Bronckers, Antonius L J J; Lyaruu, Don M; Guo, Jing et al. (2015) Composition of mineralizing incisor enamel in cystic fibrosis transmembrane conductance regulator-deficient mice. Eur J Oral Sci 123:9-16
Gansky, Stuart A; Cheng, Nancy F; Koch, Gary G (2011) Dose-Weighted Adjusted Mantel-Haenszel Tests for Numeric Scaled Strata in a Randomized Trial. Stat Biopharm Res 3:266-275
Walsh, Margaret M; Langer, Timothy J; Kavanagh, Niall et al. (2010) Smokeless tobacco cessation cluster randomized trial with rural high school males: intervention interaction with baseline smoking. Nicotine Tob Res 12:543-50
Gansky, Stuart A; Ellison, James A; Kavanagh, Catherine et al. (2009) Patterns and correlates of spit tobacco use among high school males in rural California. J Public Health Dent 69:116-24
Kim, Jae-Beom; Leucht, Philipp; Luppen, Cynthia A et al. (2007) Reconciling the roles of FAK in osteoblast differentiation, osteoclast remodeling, and bone regeneration. Bone 41:39-51
Saeki, Kuniko; Hilton, Joan F; Alliston, Tamara et al. (2007) Elevated TGF-beta2 signaling in dentin results in sex related enamel defects. Arch Oral Biol 52:814-21
Six, N; Septier, D; Chaussain-Miller, C et al. (2007) Dentonin, a MEPE fragment, initiates pulp-healing response to injury. J Dent Res 86:780-5
Weintraub, J A; Ramos-Gomez, F; Jue, B et al. (2006) Fluoride varnish efficacy in preventing early childhood caries. J Dent Res 85:172-6
Hsieh, Nancy Kwon; Herzig, Karen; Gansky, Stuart A et al. (2006) Changing dentists' knowledge, attitudes and behavior regarding domestic violence through an interactive multimedia tutorial. J Am Dent Assoc 137:596-603
Colnot, Celine (2005) Cellular and molecular interactions regulating skeletogenesis. J Cell Biochem 95:688-97

Showing the most recent 10 out of 35 publications