Abstract

The Michigan Diabetes Research and Training Center (MDRTC) is an interdisciplinary unit of the University of Michigan Medical Center. The Center exists to meet the needs of investigators and thereby support and strengthen the University's interdepartmental activities in research, training and outreach in the field of diabetes, its complications and related endocrinology and metabolism disorders. The resources provided by the Diabetes Center have expanded and enriched the base of investigators involved in diabetes research; the Center's most important resource. The Center's unique ability to orchestrate broad multidisciplinary programs fully justifies its existence. Overall goals of the Diabetes Center are to: 1. Facilitate and focus basic molecular and cellular research in the area of diabetes and related metabolic and endocrine disorders. 2. Promote the validation and application of relevant new basic knowledge in the clinical arena through rational, innovative and streamlined clinical, epidemiological and behavioral research. 3. Evaluate, refine and disseminate new clinical knowledge regarding diabetes and related disorders into community health practices, especially in those communities at increased risk. 4. Recruit, train, motivate and retain an effective manpower pool of basic and clinical investigators and health care delivery personnel in the area of diabetes, endocrinology and metabolism.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Comprehensive Center (P60)
Project #
5P60DK020572-23
Application #
6124758
Study Section
Special Emphasis Panel (ZDK1-GRB-C (O2))
Program Officer
Abraham, Kristin M
Project Start
1977-09-01
Project End
2002-11-30
Budget Start
1999-12-01
Budget End
2000-11-30
Support Year
23
Fiscal Year
2000
Total Cost
$1,881,932
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Jiang, Lin; Su, Haoran; Keogh, Julia M et al. (2018) Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression. FASEB J 32:1830-1840
Yu, Sangho; Cheng, Helia; François, Marie et al. (2018) Preoptic leptin signaling modulates energy balance independent of body temperature regulation. Elife 7:
Rumora, Amy E; Lentz, Stephen I; Hinder, Lucy M et al. (2018) Dyslipidemia impairs mitochondrial trafficking and function in sensory neurons. FASEB J 32:195-207
Xiong, Yi; Torsoni, Adriana Souza; Wu, Feihua et al. (2018) Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases. Elife 7:
Tank, E M; Figueroa-Romero, C; Hinder, L M et al. (2018) Abnormal RNA stability in amyotrophic lateral sclerosis. Nat Commun 9:2845
Liu, Yan; Jiang, Lin; Sun, Chengxin et al. (2018) Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis. Nat Commun 9:2751
Sheng, Liang; Ye, Lan; Zhang, Dong et al. (2018) New Insights Into the Long Non-coding RNA SRA: Physiological Functions and Mechanisms of Action. Front Med (Lausanne) 5:244
Zhao, Xu-Yun; Xiong, Xuelian; Liu, Tongyu et al. (2018) Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis. Nat Commun 9:2986
Dreffs, Alyssa; Henderson, Desmond; Dmitriev, Andrey V et al. (2018) Retinal pH and Acid Regulation During Metabolic Acidosis. Curr Eye Res 43:902-912
Kumar, Navasuja; Pop-Busui, Rodica; Musch, David C et al. (2018) Central Corneal Thickness Increase Due to Stromal Thickening With Diabetic Peripheral Neuropathy Severity. Cornea 37:1138-1142

Showing the most recent 10 out of 1081 publications