Abstract

The Michigan Diabetes Research and Training Center (MDRTC) is an interdisciplinary unit of the University of Michigan Medical Center. The Center exists to meet the needs of investigators and thereby support and strengthen the University's interdepartmental activities in research, training and outreach in the field of diabetes, its complications and related endocrinology and metabolism disorders. The resources provided by the Diabetes Center have expanded and enriched the base of investigators involved in diabetes research; the Center's most important resource. The Center's unique ability to orchestrate broad multidisciplinary programs fully justifies its existence. Overall goals of the Diabetes Center are to: 1. Facilitate and focus basic molecular and cellular research in the area of diabetes and related metabolic and endocrine disorders. 2. Promote the validation and application of relevant new basic knowledge in the clinical arena through rational, innovative and streamlined clinical, epidemiological and behavioral research. 3. Evaluate, refine and disseminate new clinical knowledge regarding diabetes and related disorders into community health practices, especially in those communities at increased risk. 4. Recruit, train, motivate and retain an effective manpower pool of basic and clinical investigators and health care delivery personnel in the area of diabetes, endocrinology and metabolism.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Comprehensive Center (P60)
Project #
3P60DK020572-25S1
Application #
6664910
Study Section
Special Emphasis Panel (ZDK1 (O2))
Program Officer
Abraham, Kristin M
Project Start
1977-09-01
Project End
2002-11-30
Budget Start
2001-12-01
Budget End
2002-11-30
Support Year
25
Fiscal Year
2002
Total Cost
$296,119
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Malik, Ahmed M; Miguez, Roberto A; Li, Xingli et al. (2018) Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization. Elife 7:
Lee, Pearl G; Ha, Jinkyung; Blaum, Caroline S et al. (2018) Patterns of physical activity in sedentary older individuals with type 2 diabetes. Clin Diabetes Endocrinol 4:7
Ramos, Carla J; Lin, Chengmao; Liu, Xuwen et al. (2018) The EPAC-Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability. J Biol Chem 293:717-730
Djuric, Zora; Bassis, Christine M; Plegue, Melissa A et al. (2018) Colonic Mucosal Bacteria Are Associated with Inter-Individual Variability in Serum Carotenoid Concentrations. J Acad Nutr Diet 118:606-616.e3
Vollbrecht, Peter J; Nesbitt, Kathryn M; Mabrouk, Omar S et al. (2018) Cocaine and desipramine elicit distinct striatal noradrenergic and behavioral responses in selectively bred obesity-resistant and obesity-prone rats. Behav Brain Res 346:137-143
Jiang, Lin; Su, Haoran; Keogh, Julia M et al. (2018) Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression. FASEB J 32:1830-1840
Yu, Sangho; Cheng, Helia; François, Marie et al. (2018) Preoptic leptin signaling modulates energy balance independent of body temperature regulation. Elife 7:
Rumora, Amy E; Lentz, Stephen I; Hinder, Lucy M et al. (2018) Dyslipidemia impairs mitochondrial trafficking and function in sensory neurons. FASEB J 32:195-207
Xiong, Yi; Torsoni, Adriana Souza; Wu, Feihua et al. (2018) Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases. Elife 7:
Tank, E M; Figueroa-Romero, C; Hinder, L M et al. (2018) Abnormal RNA stability in amyotrophic lateral sclerosis. Nat Commun 9:2845

Showing the most recent 10 out of 1081 publications