Abstract

The CCSCC carries out extensive educational and counseling activities for pediatric sickle cell patients and families. Programs funded by the Ohio Department of Health address the individual educational needs of children and families affected by sickle cell disease; the follow-up and enrollment in medical care of newborns with hemoglobinopathies; professional education, including an annual counselor training course: and prenatal diagnostic services. Social work services are provided by CHMC. Project 6 of this proposal, Education and Counseling Program, expands the educational goals of the CCSCC to include: a Transition Program for adolescent patients transferring from pediatric to adult care; educational programs for adult patients and families; educational sessions for parents and professionals from a patient perspective; evaluation and coordination of educational programs throughout the CCSCC. These activities will be carried out in collaboration with two community groups: the Sickle Cell Awareness Group and the Sickle Cell Parent and Family Network.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Comprehensive Center (P60)
Project #
1P60HL058421-01
Application #
6273295
Study Section
Project Start
1998-04-10
Project End
1999-03-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229

  Publications

Crosby, Lori E; Modi, Avani C; Lemanek, Kathleen L et al. (2009) Perceived barriers to clinic appointments for adolescents with sickle cell disease. J Pediatr Hematol Oncol 31:571-6
Crable, Scott C; Hammond, Suzan M; Papes, Richard et al. (2005) Multiple isoforms of the KC1 cotransporter are expressed in sickle and normal erythroid cells. Exp Hematol 33:624-31
Zhou, Guo-Ping; Wong, Clara; Su, Robert et al. (2004) Human potassium chloride cotransporter 1 (SLC12A4) promoter is regulated by AP-2 and contains a functional downstream promoter element. Blood 103:4302-9
Yasin, Zahida; Witting, Scott; Palascak, Mary B et al. (2003) Phosphatidylserine externalization in sickle red blood cells: associations with cell age, density, and hemoglobin F. Blood 102:365-70
Merciris, P; Claussen, W J; Joiner, C H et al. (2003) Regulation of K-Cl cotransport by Syk and Src protein tyrosine kinases in deoxygenated sickle cells. Pflugers Arch 446:232-8
Holtzclaw, J David; Jiang, Maorong; Yasin, Zahida et al. (2002) Rehydration of high-density sickle erythrocytes in vitro. Blood 100:3017-25
Joiner, C H; Jiang, M; Claussen, W J et al. (2001) Dipyridamole inhibits sickling-induced cation fluxes in sickle red blood cells. Blood 97:3976-83
Joiner, C H; Franco, R S (2001) The activation of KCL cotransport by deoxygenation and its role in sickle cell dehydration. Blood Cells Mol Dis 27:158-64
Franco, R S; Yasin, Z; Lohmann, J M et al. (2000) The survival characteristics of dense sickle cells. Blood 96:3610-7