Persistent and pronounced differences in health by race/ethnicity (often termed health disparities) exist for multiple health outcomes. Despite repeated documentation of these disparities, there is still substantial debate on the driving forces behind them. Identifying the factors that generate these disparities has obvious implications for interventions and policies to improve health in minority populations and reduce disparities. There is a growing sense that current approaches to understanding these disparities, which often attempt to fragment the problem into distinct social and biological components, are insufficient, not only from the point of view of scientific understanding, but also from the point of view of identifying the most effective strategies to reduce disparities in the real world. Understanding health disparities will require integration of social and biological factors; as well as consideration, not only of individual characteristics, but also characteristics of the multiple contexts in which individuals live and work. The overarching goal of the Michigan Center for Integrative Approaches to Health Disparities (CIAHD) is to promote and support research that comprehensively integrates social and biological factors within a multilevel framework in understanding the determinants of minority health and health disparities. Although the center will initially focus on applying this model to cardiovascular risk, it provides a framework useful to all minority health and health disparities researchers. This multilevel integrated approach is crucial to identifying the interventions and strategies most likely to improve minority health and reduce health disparities. This overarching goal will be achieved through a set of interrelated Aims.
Aim 1. To advance scientific understanding of how the interrelation of social and biologic factors contributes to health in minority populations and health disparities with a specific focus on cardiovascular risk.
Aim 2. To establish a mutually beneficial partnership between the University of Michigan and the Jackson Heart Study (JHS) (through its partners Jackson State University and the University of Mississippi Medical Center) to advance research and training within our multilevel integrated framework.
Aim 3. To create a forum that will integrate and centralize ongoing minority health and health disparities research broadly at the University of Michigan and our partner institutions under the general umbrella of a multilevel framework that integrates social and biological factors.
Aim 4. To disseminate the multilevel integrated paradigm to the biomedical and health research community, as well as to the public generally.
These aims will be achieved through an Administrative Core and a Research Core. The Administrative Core will provide leadership and coordination and will organize training, as well as intra-and-inter-institutional exchanges. The Research Core will include three research projects linked to the overall theme (one of which is a partnership between the University of Michigan and JHS), pilot projects, and statistical support. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Minority Health and Health Disparities (NIMHD)
Type
Comprehensive Center (P60)
Project #
1P60MD002249-01
Application #
7276921
Study Section
Special Emphasis Panel (ZMD1-LW (07))
Program Officer
Castille, Dorothy M
Project Start
2007-09-11
Project End
2012-08-31
Budget Start
2007-09-11
Budget End
2008-08-31
Support Year
1
Fiscal Year
2007
Total Cost
$1,409,295
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Mayne, Stephanie L; Moore, Kari A; Powell-Wiley, Tiffany M et al. (2018) Longitudinal Associations of Neighborhood Crime and Perceived Safety With Blood Pressure: The Multi-Ethnic Study of Atherosclerosis (MESA). Am J Hypertens 31:1024-1032
Jones, Sydney A; Li, Quefeng; Aiello, Allison E et al. (2018) Physical Activity, Sedentary Behavior, and Retirement: The Multi-Ethnic Study of Atherosclerosis. Am J Prev Med 54:786-794
Ward, Melanie; Schulz, Amy J; Israel, Barbara A et al. (2018) A conceptual framework for evaluating health equity promotion within community-based participatory research partnerships. Eval Program Plann 70:25-34
Hussein, Mustafa; Diez Roux, Ana V; Mujahid, Mahasin S et al. (2018) Unequal Exposure or Unequal Vulnerability? Contributions of Neighborhood Conditions and Cardiovascular Risk Factors to Socioeconomic Inequality in Incident Cardiovascular Disease in the Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol 187:1424-1437
Ward, Julia B; Robinson, Whitney R; Pence, Brian W et al. (2018) Educational Mobility Across Generations and Depressive Symptoms Over 10 Years Among US Latinos. Am J Epidemiol :
Cardel, Michelle I; Min, Yuan-I; Sims, Mario et al. (2018) Association of psychosocial stressors with metabolic syndrome severity among African Americans in the Jackson Heart Study. Psychoneuroendocrinology 90:141-147
Dong, Liming; Freedman, Vicki A; Sánchez, Brisa N et al. (2018) Racial and ethnic differences in disability transitions among older adults in the United States. J Gerontol A Biol Sci Med Sci :
Brenner, Allison B; Diez-Roux, Ana V; Gebreab, Samson Y et al. (2018) The Epidemiology of Coping in African American Adults in the Jackson Heart Study (JHS). J Racial Ethn Health Disparities 5:978-994
Kern, David M; Auchincloss, Amy H; Stehr, Mark F et al. (2018) Neighborhood price of healthier food relative to unhealthy food and its association with type 2 diabetes and insulin resistance: The multi-ethnic study of atherosclerosis. Prev Med 106:122-129
Lê-Scherban, Félice; Brenner, Allison B; Hicken, Margaret T et al. (2018) Child and Adult Socioeconomic Status and the Cortisol Response to Acute Stress: Evidence From the Multi-Ethnic Study of Atherosclerosis. Psychosom Med 80:184-192

Showing the most recent 10 out of 192 publications