Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA005868-14
Application #
2043361
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1983-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1998-03-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Pharmacology
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Draski, L J; Bice, P J; Deitrich, R A (2001) Developmental alterations of ethanol sensitivity in selectively bred high and low alcohol sensitive rats. Pharmacol Biochem Behav 70:387-96
Draski, L J; Deitrich, R A; Menez, J F (1997) Phenobarbital sensitivity in HAS and LAS rats before and after chronic administration of ethanol. Pharmacol Biochem Behav 57:651-7
Kiefer, S W; Badia-Elder, N E (1997) Taste reactivity in high-alcohol-sensitive and low-alcohol-sensitive rats. Alcohol 14:225-9
Pearson, B J; Donatelli, D P; Freund, R K et al. (1997) Differential development and characterization of rapid acute neuronal tolerance to the depressant effects of ethanol on cerebellar Purkinje neurons of low-alcohol-sensitive and high-alcohol-sensitive rats. J Pharmacol Exp Ther 280:739-46
Erwin, V G; Draski, L J; Deitrich, R A (1996) Neurotensin levels and receptors in HAS and LAS rat brains: effects of ethanol. Pharmacol Biochem Behav 54:525-32
Zimatkin, S M; Deitrich, R A (1995) Aldehyde dehydrogenase activities in the brains of rats and mice genetically selected for different sensitivity to alcohol. Alcohol Clin Exp Res 19:1300-6
Liu, Y; Fay, T; Deitrich, R A (1995) Behavioral effects and pharmacokinetics of propofol in rats selected for differential ethanol sensitivity. Alcohol Clin Exp Res 19:874-8
Deitrich, R A; Draski, L J; Baker, R C (1994) Effect of pentobarbital and gaseous anesthetics on rats selectively bred for ethanol sensitivity. Pharmacol Biochem Behav 47:721-5
Deitrich, R A (1993) Selective breeding for initial sensitivity to ethanol. Behav Genet 23:153-62
Menez, J F; Machu, T K; Song, B J et al. (1993) Phosphorylation of cytochrome P4502E1 (CYP2E1) by calmodulin dependent protein kinase, protein kinase C and cAMP dependent protein kinase. Alcohol Alcohol 28:445-51

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