Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA006661-10
Application #
2043527
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1985-03-01
Project End
1999-12-30
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Missouri-Columbia
Department
Biochemistry
Type
Schools of Medicine
DUNS #
112205955
City
Columbia
State
MO
Country
United States
Zip Code
65211
Simonyi, Agnes; Christian, Michael R; Sun, Albert Y et al. (2004) Chronic ethanol-induced subtype- and subregion-specific decrease in the mRNA expression of metabotropic glutamate receptors in rat hippocampus. Alcohol Clin Exp Res 28:1419-23
Xu, J; Chalimoniuk, M; Shu, Y et al. (2003) Prostaglandin E2 production in astrocytes: regulation by cytokines, extracellular ATP, and oxidative agents. Prostaglandins Leukot Essent Fatty Acids 69:437-48
Xu, Jianfeng; Yu, Sue; Sun, Albert Y et al. (2003) Oxidant-mediated AA release from astrocytes involves cPLA(2) and iPLA(2). Free Radic Biol Med 34:1531-43
Xu, Jianfeng; Weng, Yu-I; Simonyi, Agnes et al. (2002) Role of PKC and MAPK in cytosolic PLA2 phosphorylation and arachadonic acid release in primary murine astrocytes. J Neurochem 83:259-70
Simonyi, Agnes; Woods, Danielle; Sun, Albert Y et al. (2002) Grape polyphenols inhibit chronic ethanol-induced COX-2 mRNA expression in rat brain. Alcohol Clin Exp Res 26:352-7
Wang, Qun; Xu, Jianfeng; Rottinghaus, George E et al. (2002) Resveratrol protects against global cerebral ischemic injury in gerbils. Brain Res 958:439-47
Dixon, Joseph L; Shen, Siming; Vuchetich, James P et al. (2002) Increased atherosclerosis in diabetic dyslipidemic swine: protection by atorvastatin involves decreased VLDL triglycerides but minimal effects on the lipoprotein profile. J Lipid Res 43:1618-29
Sun, Albert Y; Simonyi, Agnes; Sun, Grace Y (2002) The ""French Paradox"" and beyond: neuroprotective effects of polyphenols. Free Radic Biol Med 32:314-8
Wang, J H; Sun, G Y (2001) Ethanol inhibits cytokine-induced iNOS and sPLA2 in immortalized astrocytes: evidence for posttranscriptional site of ethanol action. J Biomed Sci 8:126-33
Sun, A Y; Sun, G Y (2001) Ethanol and oxidative mechanisms in the brain. J Biomed Sci 8:37-43

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