Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA007261-12
Application #
2043773
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1992-07-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
009214214
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Mic, Felix A; Haselbeck, Robert J; Cuenca, Arnold E et al. (2002) Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice. Development 129:2271-82
Duester, G (2001) Genetic dissection of retinoid dehydrogenases. Chem Biol Interact 130-132:469-80
Hoffmann, I; Ang, H L; Duester, G (1998) Alcohol dehydrogenases in Xenopus development: conserved expression of ADH1 and ADH4 in epithelial retinoid target tissues. Dev Dyn 213:261-70
Haselbeck, R J; Duester, G (1998) ADH1 and ADH4 alcohol/retinol dehydrogenases in the developing adrenal blastema provide evidence for embryonic retinoid endocrine function. Dev Dyn 213:114-20
Haselbeck, R J; Duester, G (1998) ADH4-lacZ transgenic mouse reveals alcohol dehydrogenase localization in embryonic midbrain/hindbrain, otic vesicles, and mesencephalic, trigeminal, facial, and olfactory neural crest. Alcohol Clin Exp Res 22:1607-13
Duester, G; Deltour, L; Ang, H L (1997) Evidence that class IV alcohol dehydrogenase may function in embryonic retinoic acid synthesis. Adv Exp Med Biol 414:357-64
Haselbeck, R J; Ang, H L; Duester, G (1997) Class IV alcohol/retinol dehydrogenase localization in epidermal basal layer: potential site of retinoic acid synthesis during skin development. Dev Dyn 208:447-53
Ang, H L; Duester, G (1997) Initiation of retinoid signaling in primitive streak mouse embryos: spatiotemporal expression patterns of receptors and metabolic enzymes for ligand synthesis. Dev Dyn 208:536-43
Satre, M A; Zgombic-Knight, M; Duester, G (1994) The complete structure of human class IV alcohol dehydrogenase (retinol dehydrogenase) determined from the ADH7 gene. J Biol Chem 269:15606-12
Duester, G (1994) Retinoids and the alcohol dehydrogenase gene family. EXS 71:279-90

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