Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
5R01AA009000-06
Application #
2045026
Study Section
Biochemistry, Physiology and Medicine Subcommittee (ALCB)
Project Start
1991-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Kelly, M P; Stein, J M; Vecsey, C G et al. (2009) Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Galphas, a G-protein subunit genetically linked to schizophrenia. Mol Psychiatry 14:398-415, 347
Kelly, Michele P; Cheung, York-Fong; Favilla, Christopher et al. (2008) Constitutive activation of the G-protein subunit Galphas within forebrain neurons causes PKA-dependent alterations in fear conditioning and cortical Arc mRNA expression. Learn Mem 15:75-83
Yang, Xiaoju; Wang, Shelun; Rice, Kenner C et al. (2008) Restraint stress and ethanol consumption in two mouse strains. Alcohol Clin Exp Res 32:840-52
Kelly, Michele P; Isiegas, Carolina; Cheung, York-Fong et al. (2007) Constitutive activation of Galphas within forebrain neurons causes deficits in sensorimotor gating because of PKA-dependent decreases in cAMP. Neuropsychopharmacology 32:577-88
Germain-Lee, Emily L; Schwindinger, William; Crane, Janet L et al. (2005) A mouse model of albright hereditary osteodystrophy generated by targeted disruption of exon 1 of the Gnas gene. Endocrinology 146:4697-709
Chandler, L Judson; Bonci, Antonello; Wand, Gary S et al. (2004) Recent advances in cyclic-adenosine monophosphate/protein kinase A signaling in ethanol-induced synaptic and behavioral alterations. Alcohol Clin Exp Res 28:1129-36
Yang, Xioaju; Oswald, Lynn; Wand, Gary (2003) The cyclic AMP/protein kinase A signal transduction pathway modulates tolerance to sedative and hypothermic effects of ethanol. Alcohol Clin Exp Res 27:1220-5
Wand, G; Levine, M; Zweifel, L et al. (2001) The cAMP-protein kinase A signal transduction pathway modulates ethanol consumption and sedative effects of ethanol. J Neurosci 21:5297-303
Yang, X; Wand, G (2000) Ethanol uses cAMP-independent signal transduction mechanisms to activate proenkephalin promoter activity in rat C6 glioma cells. Alcohol Clin Exp Res 24:952-7
Yang, X; Horn, K; Wand, G S (1998) Chronic ethanol exposure impairs phosphorylation of CREB and CRE-binding activity in rat striatum. Alcohol Clin Exp Res 22:382-90

Showing the most recent 10 out of 24 publications