This application to PA-14-190 (Epidemiology and Prevention in Alcohol Research (R01)) continues research to reduce college students' alcohol use and consequences (R01AA012547; Larimer PI). Development of efficacious college drinking interventions is an important public health priority. Personalized feedback interventions (PFI), delivered via mail, internet, cell-phone, and text messaging, have evidence of efficacy but effects are small and variable across time and outcomes. Remote PFI delivery increases reach, but introduces barriers to efficacy, particularly variable attention to and comprehension of material. PFIs with multiple components delivered simultaneously may be overwhelming or confusing. This is problematic, as highly personalized feedback interventions with more components may produce larger and longer effects. In contrast, short-term efficacy of single-component PFIs (e.g., normative feedback) has been established, and these simpler PFIs may have more immediate impact; however, duration has been variable. Research is needed to determine optimal delivery to capitalize on clarity and initial impact of single-component and greater effect size and duration of multi-component PFIs. Duration may also be impacted by fluctuations in drinking during high- risk events. Moreover, PFI effects may be attenuated by timing of assessments relative to important high-risk events (e.g., New Year's eve falling within assessment of past month drinking), as well as time elapsed between PFI and specific events and if the PFI addressed the high-risk event. Providing boosters to address high-risk events, assessing drinking during these events and on typical occasions, and evaluating impact of intervention and assessment timing relative to high-risk events may help explain inconsistent findings regarding PFI effect size and duration. The current study addresses these gaps through evaluating a multi- component online PFI with simultaneous delivery (all PFI components at once) versus a sequential format, wherein individual PFI components are delivered one at a time to minimize attention demands for each component. The study seeks to enhance magnitude and duration of effects through adding text-message- based boosters to address specific high-risk events during the year following intervention. We will assess event-specific and typical drinking and consequences to evaluate immediate and sustained (through 24 months) changes in mediators and outcomes. Participants (N=1000 heavy drinking students) will be recruited in 4 cohorts corresponding with each quarter of the calendar year, and randomly assigned in a 2 (simultaneous versus sequential PFI) x 2 (boosters or no boosters) +1 (Assessment Only Control) longitudinal RCT design.
Specific aims are: 1)Evaluate efficacy, moderators, and mediators of multi-component PFI, comparing simultaneous vs. sequential delivery vs. AOC; 2) Evaluate impact, mediators, and moderators of event-specific boosters on outcomes for both typical and event-specific drinking; 3) Evaluate timing of high-risk events relative to time since initial PFI and timing of longitudinal follow-up assessments on intervention efficacy.

Public Health Relevance

Alcohol use is associated with significant harm in college populations, including all three leading causes of death (accidents, suicide, homicide). The current application continues a program of research to reduce alcohol use and consequences among college students, and seeks to enhance efficacy, effect sizes, and duration of electronic screening and brief interventions for this population through evaluating optimal program delivery (simultaneous or sequential) for personalized feedback interventions (PFIs), text-message boosters targeting high-risk drinking events, and impact of intervention and assessment timing on outcomes. Answers to these questions will have immediate implications for dissemination and implementation on campuses nationwide to address alcohol-related harm.

National Institute of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Research Project (R01)
Project #
Application #
Study Section
Interventions to Prevent and Treat Addictions Study Section (IPTA)
Program Officer
Scott, Marcia S
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Washington
Schools of Arts and Sciences
United States
Zip Code
LaBrie, Joseph W; Earle, Andrew M; Hummer, Justin F et al. (2016) Is Prepartying a Cause of Heavy Drinking and Consequences Rather Than Just a Correlate? A Longitudinal Look at the Relationship Between Prepartying, Alcohol Approval, and Subsequent Drinking and Consequences. Subst Use Misuse 51:1013-23
Montes, Kevin S; LaBrie, Joseph W; Froidevaux, Nicole M (2016) Do Protective Behavioral Strategies Mediate the Effect of Preparty Motives on Event-Level Preparty Alcohol Use? Subst Use Misuse 51:1047-55
Krieger, Heather; Neighbors, Clayton; Lewis, Melissa A et al. (2016) Injunctive Norms and Alcohol Consumption: A Revised Conceptualization. Alcohol Clin Exp Res 40:1083-92
Lewis, Melissa A; Litt, Dana M; Neighbors, Clayton (2015) The Chicken or the Egg: Examining Temporal Precedence Among Attitudes, Injunctive Norms, and College Student Drinking. J Stud Alcohol Drugs 76:594-601
Kenney, Shannon R; Lac, Andrew; Hummer, Justin F et al. (2014) Development and validation of the Hookup Motives Questionnaire (HMQ). Psychol Assess 26:1127-37
Napper, Lucy E; Kenney, Shannon R; Lac, Andrew et al. (2014) A cross-lagged panel model examining protective behavioral strategies: are types of strategies differentially related to alcohol use and consequences? Addict Behav 39:480-6
Kenney, Shannon R; Napper, Lucy E; LaBrie, Joseph W (2014) Social anxiety and drinking refusal self-efficacy moderate the relationship between drinking game participation and alcohol-related consequences. Am J Drug Alcohol Abuse 40:388-94
Kenney, Shannon R; Paves, Andrew P; Grimaldi, Elizabeth M et al. (2014) Sleep quality and alcohol risk in college students: examining the moderating effects of drinking motives. J Am Coll Health 62:301-8
Labrie, Joseph W; Hummer, Justin F; Ghaidarov, Tehniat M et al. (2014) Hooking up in the college context: the event-level effects of alcohol use and partner familiarity on hookup behaviors and contentment. J Sex Res 51:62-73
Ehret, Phillip J; Ghaidarov, Tehniat M; LaBrie, Joseph W (2013) Can you say no? Examining the relationship between drinking refusal self-efficacy and protective behavioral strategy use on alcohol outcomes. Addict Behav 38:1898-904

Showing the most recent 10 out of 58 publications