Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
3R01AG000424-31S1
Application #
3114062
Study Section
Nutrition Study Section (NTN)
Project Start
1978-06-01
Project End
1997-04-30
Budget Start
1993-09-30
Budget End
1994-04-30
Support Year
31
Fiscal Year
1993
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Aid, Saba; Bosetti, Francesca (2007) Gene expression of cyclooxygenase-1 and Ca(2+)-independent phospholipase A(2) is altered in rat hippocampus during normal aging. Brain Res Bull 73:108-13
Weerasinghe, Gayani R; Coon, Steven L; Bhattacharjee, Abesh Kumar et al. (2006) Regional protein levels of cytosolic phospholipase A2 and cyclooxygenase-2 in Rhesus monkey brain as a function of age. Brain Res Bull 69:614-21
Walford, R L; Bechtel, R; MacCallum, T et al. (1996) ""Biospheric medicine"" as viewed from the two-year first closure of Biosphere 2. Aviat Space Environ Med 67:609-17
Harris, S B; Gunion, M W; Rosenthal, M J et al. (1994) Serum glucose, glucose tolerance, corticosterone and free fatty acids during aging in energy restricted mice. Mech Ageing Dev 73:209-21
Effros, R B; Boucher, N; Porter, V et al. (1994) Decline in CD28+ T cells in centenarians and in long-term T cell cultures: a possible cause for both in vivo and in vitro immunosenescence. Exp Gerontol 29:601-9
Walford, R L; Harris, S B; Gunion, M W (1992) The calorically restricted low-fat nutrient-dense diet in Biosphere 2 significantly lowers blood glucose, total leukocyte count, cholesterol, and blood pressure in humans. Proc Natl Acad Sci U S A 89:11533-7
May, P C; Telford, N; Salo, D et al. (1992) Failure of dietary restriction to retard age-related neurochemical changes in mice. Neurobiol Aging 13:787-91
Effros, R B; Svoboda, K; Walford, R L (1991) Influence of age and caloric restriction on macrophage IL-6 and TNF production. Lymphokine Cytokine Res 10:347-51
Fu, C S; Harris, S B; Wilhelmi, P et al. (1991) Lack of effect of age and dietary restriction on DNA single-stranded breaks in brain, liver, and kidney of (C3H x C57BL/10)F1 mice. J Gerontol 46:B78-80
Spindler, S R; Grizzle, J M; Walford, R L et al. (1991) Aging and restriction of dietary calories increases insulin receptor mRNA, and aging increases glucocorticoid receptor mRNA in the liver of female C3B10RF1 mice. J Gerontol 46:B233-7

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