Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG006036-11
Application #
2049429
Study Section
Biopsychology Study Section (BPO)
Project Start
1985-12-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Neurosciences
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Arnsten, Amy F T; Pliszka, Steven R (2011) Catecholamine influences on prefrontal cortical function: relevance to treatment of attention deficit/hyperactivity disorder and related disorders. Pharmacol Biochem Behav 99:211-6
Arnsten, Amy F T (2011) Catecholamine influences on dorsolateral prefrontal cortical networks. Biol Psychiatry 69:e89-99
Arnsten, Amy F T (2011) Prefrontal cortical network connections: key site of vulnerability in stress and schizophrenia. Int J Dev Neurosci 29:215-23
Arnsten, Amy F T; Paspalas, Constantinos D; Gamo, Nao J et al. (2010) Dynamic Network Connectivity: A new form of neuroplasticity. Trends Cogn Sci 14:365-75
Salloway, S; Sperling, R; Gilman, S et al. (2009) A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology 73:2061-70
Arnsten, Amy F T (2009) Stress signalling pathways that impair prefrontal cortex structure and function. Nat Rev Neurosci 10:410-22
Robbins, T W; Arnsten, A F T (2009) The neuropsychopharmacology of fronto-executive function: monoaminergic modulation. Annu Rev Neurosci 32:267-87
Ramos, Brian P; Stark, David; Verduzco, Luis et al. (2006) Alpha2A-adrenoceptor stimulation improves prefrontal cortical regulation of behavior through inhibition of cAMP signaling in aging animals. Learn Mem 13:770-6
Arnsten, Amy F T; Ramos, Brian P; Birnbaum, Shari G et al. (2005) Protein kinase A as a therapeutic target for memory disorders: rationale and challenges. Trends Mol Med 11:121-8
Birnbaum, S G; Yuan, P X; Wang, M et al. (2004) Protein kinase C overactivity impairs prefrontal cortical regulation of working memory. Science 306:882-4

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