Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG006943-10
Application #
2049638
Study Section
Pathology A Study Section (PTHA)
Project Start
1987-02-01
Project End
1998-08-31
Budget Start
1996-07-01
Budget End
1998-08-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Picower Institute for Medical Research
Department
Type
DUNS #
City
Manhasset
State
NY
Country
United States
Zip Code
11030
Li, J J; Dickson, D; Hof, P R et al. (1998) Receptors for advanced glycosylation endproducts in human brain: role in brain homeostasis. Mol Med 4:46-60
Koschinsky, T; He, C J; Mitsuhashi, T et al. (1997) Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy. Proc Natl Acad Sci U S A 94:6474-9
Stitt, A W; Li, Y M; Gardiner, T A et al. (1997) Advanced glycation end products (AGEs) co-localize with AGE receptors in the retinal vasculature of diabetic and of AGE-infused rats. Am J Pathol 150:523-31
Stitt, A W; He, C; Friedman, S et al. (1997) Elevated AGE-modified ApoB in sera of euglycemic, normolipidemic patients with atherosclerosis: relationship to tissue AGEs. Mol Med 3:617-27
Fishbane, S; Bucala, R; Pereira, B J et al. (1997) Reduction of plasma apolipoprotein-B by effective removal of circulating glycation derivatives in uremia. Kidney Int 52:1645-50
Li, Y M; Steffes, M; Donnelly, T et al. (1996) Prevention of cardiovascular and renal pathology of aging by the advanced glycation inhibitor aminoguanidine. Proc Natl Acad Sci U S A 93:3902-7
Li, Y M; Mitsuhashi, T; Wojciechowicz, D et al. (1996) Molecular identity and cellular distribution of advanced glycation endproduct receptors: relationship of p60 to OST-48 and p90 to 80K-H membrane proteins. Proc Natl Acad Sci U S A 93:11047-52
Bucala, R; Vlassara, H (1995) Advanced glycosylation end products in diabetic renal and vascular disease. Am J Kidney Dis 26:875-88
Zimmerman, G A; Meistrell 3rd, M; Bloom, O et al. (1995) Neurotoxicity of advanced glycation endproducts during focal stroke and neuroprotective effects of aminoguanidine. Proc Natl Acad Sci U S A 92:3744-8
Vlassara, H; Li, Y M; Imani, F et al. (1995) Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): a new member of the AGE-receptor complex. Mol Med 1:634-46

Showing the most recent 10 out of 22 publications