Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
3R01AG008796-07S1
Application #
2612501
Study Section
Neuropharmacology and Neurochemistry Review Committee (NPNC)
Project Start
1990-03-01
Project End
1999-06-30
Budget Start
1997-08-01
Budget End
1998-06-30
Support Year
7
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Anatomy/Cell Biology
Type
Schools of Dentistry
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Simkin, Dina; Hattori, Shoai; Ybarra, Natividad et al. (2015) Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression. J Neurosci 35:13206-18
Núñez-Santana, Félix Luis; Oh, Myongsoo Matthew; Antion, Marcia Diana et al. (2014) Surface L-type Ca2+ channel expression levels are increased in aged hippocampus. Aging Cell 13:111-20
Fortier, Catherine B; Leritz, Elizabeth C; Salat, David H et al. (2014) Widespread effects of alcohol on white matter microstructure. Alcohol Clin Exp Res 38:2925-33
Oh, M Matthew; Oliveira, Fernando A; Waters, Jack et al. (2013) Altered calcium metabolism in aging CA1 hippocampal pyramidal neurons. J Neurosci 33:7905-11
McKay, Bridget M; Oh, M Matthew; Disterhoft, John F (2013) Learning increases intrinsic excitability of hippocampal interneurons. J Neurosci 33:5499-506
Fortier, Catherine B; Leritz, Elizabeth C; Salat, David H et al. (2011) Reduced cortical thickness in abstinent alcoholics and association with alcoholic behavior. Alcohol Clin Exp Res 35:2193-201
Burgdorf, Jeffrey; Zhang, Xiao-lei; Weiss, Craig et al. (2011) The N-methyl-D-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats. Neurobiol Aging 32:698-706
Sametsky, Evgeny A; Disterhoft, John F; Geinisman, Yuri et al. (2010) Synaptic strength and postsynaptically silent synapses through advanced aging in rat hippocampal CA1 pyramidal neurons. Neurobiol Aging 31:813-25
Oh, M Matthew; McKay, Bridget M; Power, John M et al. (2009) Learning-related postburst afterhyperpolarization reduction in CA1 pyramidal neurons is mediated by protein kinase A. Proc Natl Acad Sci U S A 106:1620-5
McGlinchey, Regina E; Capozzi, Stephen M; Fortier, Catherine Brawn et al. (2008) Procedural memory system supports single cue trace eyeblink conditioning in medial temporal lobe amnesia. Neuropsychology 22:278-82

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