Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
7R01AG009453-02
Application #
3121313
Study Section
Pathology A Study Section (PTHA)
Project Start
1992-01-15
Project End
1996-12-31
Budget Start
1992-01-15
Budget End
1992-12-31
Support Year
2
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Picower Institute for Medical Research
Department
Type
DUNS #
City
Manhasset
State
NY
Country
United States
Zip Code
11030
Schulman, Carl I; Uribarri, Jaime; Cai, Weijing et al. (2014) Increased circulating advanced glycation endproducts (AGEs) in acute trauma patients. Clin Chem Lab Med 52:103-8
Uribarri, Jaime; Cai, Weijing; Pyzik, Renata et al. (2014) Suppression of native defense mechanisms, SIRT1 and PPAR?, by dietary glycoxidants precedes disease in adult humans; relevance to lifestyle-engendered chronic diseases. Amino Acids 46:301-9
Vlassara, Helen; Uribarri, Jaime (2014) Advanced glycation end products (AGE) and diabetes: cause, effect, or both? Curr Diab Rep 14:453
Cai, Weijing; Ramdas, Maya; Zhu, Li et al. (2012) Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1. Proc Natl Acad Sci U S A 109:15888-93
Uribarri, Jaime; Cai, Weijing; Ramdas, Maya et al. (2011) Restriction of advanced glycation end products improves insulin resistance in human type 2 diabetes: potential role of AGER1 and SIRT1. Diabetes Care 34:1610-6
Uribarri, Jaime; Woodruff, Sandra; Goodman, Susan et al. (2010) Advanced glycation end products in foods and a practical guide to their reduction in the diet. J Am Diet Assoc 110:911-16.e12
Cai, Weijing; He, John Cijiang; Zhu, Li et al. (2008) AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation. Am J Physiol Cell Physiol 294:C145-52
Peppa, Melpomeni; Uribarri, Jaime; Vlassara, Helen (2008) Aging and glycoxidant stress. Hormones (Athens) 7:123-32
Vlassara, Helen; Uribarri, Jaime; Cai, Weijing et al. (2008) Advanced glycation end product homeostasis: exogenous oxidants and innate defenses. Ann N Y Acad Sci 1126:46-52
Linden, Ellena; Cai, Weijing; He, John C et al. (2008) Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation. Clin J Am Soc Nephrol 3:691-8

Showing the most recent 10 out of 44 publications