T Cell Maturation and Thymic Activity in the Aged

Thoman, Marilyn L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Aging (NIA)
• Type: Research Project (R01)
• Project #: 2R01AG009948-07
• Application #: 6400415
• Study Section: Geriatrics and Rehabilitation Medicine (GRM)
• Program Officer: Fuldner, Rebecca A
• Project Start: 1997-09-30
• Project End: 2006-07-31
• Budget Start: 2001-09-01
• Budget End: 2002-07-31
• Support Year: 7
• Fiscal Year: 2001
• Total Cost: $384,817

Institution

• Name: Sidney Kimmel Cancer Center
• City: San Diego
• State: CA
• Country: United States
• Zip Code: 92121

Publications

Mu, X Y; Thoman, M L (2000) Aging affects the regeneration of the CD8+ T cell compartment in bone marrow transplanted mice. Mech Ageing Dev 112:113-24

Timm, J A; Thoman, M L (1999) Maturation of CD4+ lymphocytes in the aged microenvironment results in a memory-enriched population. J Immunol 162:711-7

Mu, X Y; Thoman, M L (1999) The age-dependent cytokine production by murine CD8+ T cells as determined by four-color flow cytometry analysis. J Gerontol A Biol Sci Med Sci 54:B116-23

Thoman, M L (1997) Early steps in T cell development are affected by aging. Cell Immunol 178:117-23

Thoman, M L (1995) The pattern of T lymphocyte differentiation is altered during thymic involution. Mech Ageing Dev 82:155-70