The purpose of this research is to develop a multidimensional psychometric test instrument to assess cognitive functioning in the elderly which will have equivalent English and Spanish versions. Statistical methods associated with Item Response Theory (IRT) will be used for test development, and an important goal of this project will be to test the efficacy of these methods for multilingual neuropsychological test development. Homogeneous scales which assess broad ability ranges applicable to both patients with moderately severe dementia and high functioning normals will be developed. The scales will measure 12 abilities that have been shown to be important in neuropsychological and cognitive research with the elderly. Scales will be matched according to important psychometric characteristics to facilitate assessment of differential patterns of cognitive deficit independent of psychometric artifact. IRT procedures will be used in test construction to minimize cultural and language bias of items and to construct provisional norms for the final scales. Test development will be based upon a sample of 400 normal elderly (200 English speaking and 200 Spanish speaking). In addition, a group of dementia patients and a group of high functioning, non-elderly normals will be used to assure that items are included which will provide low and high end discrimination for all of the abilities assessed. This will be a three year project. Item development and pilot testing will occur during months 1 to 6. Recruitment and testing of the normal elderly derivation. sample will occur during months 7 to 30. Statistical analysis, item selection, calculation of provisional norms, and evaluation of efficacy of test development procedures will be completed during months 31 to 36.
| Fletcher, Evan; Gavett, Brandon; Harvey, Danielle et al. (2018) Brain volume change and cognitive trajectories in aging. Neuropsychology 32:436-449 |
| Gavett, Brandon E; Fletcher, Evan; Harvey, Danielle et al. (2018) Ethnoracial differences in brain structure change and cognitive change. Neuropsychology 32:529-540 |
| Mungas, Dan; Early, Dawnté R; Glymour, M Maria et al. (2018) Education, bilingualism, and cognitive trajectories: Sacramento Area Latino Aging Study (SALSA). Neuropsychology 32:77-88 |
| Mungas, Dan; Gavett, Brandon; Fletcher, Evan et al. (2018) Education amplifies brain atrophy effect on cognitive decline: implications for cognitive reserve. Neurobiol Aging 68:142-150 |
| Maillard, Pauline; Carmichael, Owen T; Reed, Bruce et al. (2015) Cooccurrence of vascular risk factors and late-life white-matter integrity changes. Neurobiol Aging 36:1670-1677 |
| Melrose, Rebecca J; Brewster, Paul; Marquine, María J et al. (2015) Early life development in a multiethnic sample and the relation to late life cognition. J Gerontol B Psychol Sci Soc Sci 70:519-31 |
| Lau, Karen M; Parikh, Mili; Harvey, Danielle J et al. (2015) Early Cognitively Based Functional Limitations Predict Loss of Independence in Instrumental Activities of Daily Living in Older Adults. J Int Neuropsychol Soc 21:688-98 |
| Ober, Beth A; Shenaut, Gregory K (2014) Repetition priming of words and nonwords in Alzheimer's disease and normal aging. Neuropsychology 28:973-83 |
| Brewster, Paul W H; Melrose, Rebecca J; Marquine, María J et al. (2014) Life experience and demographic influences on cognitive function in older adults. Neuropsychology 28:846-58 |
| Heaton, Robert K; Akshoomoff, Natacha; Tulsky, David et al. (2014) Reliability and validity of composite scores from the NIH Toolbox Cognition Battery in adults. J Int Neuropsychol Soc 20:588-98 |
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