The purpose of this epidemiologic study is to measure the prevalence of hearing loss and evaluate the relationships of hearing loss and functional changes in the peripheral auditory system to age in a population-based study of middle and older-aged adults. The large (n=4,363) cohort of adults, 48-89 years of age living in Beaver Dam, Wisconsin, will be examined using standardized protocols. Hearing sensitivity, speech recognition, middle-ear function and hair-cell integrity will be measured. A standardized questionnaire about ototoxic drug exposures, noise exposure (adapted from previous epidemiologic studies) and the functional impact of hearing impairment will be administered. This population is already participating in the Beaver Dam Eye Study, an incidence study of age-related ocular disorders. We will use data collected concurrently as part of the eye study, and previously collected data from examinations five years ago, to assess the relationships of diabetes, hypertension, cardiovascular disease and its risk factors (total cholesterol, HDL, smoking, blood pressure, and dietary intake of saturated fat and cholesterol) to age-related decreased hearing sensitivity. We will also measure the 2.5 year incidence and progression of hearing loss in persons over 75 years of age and examine risk factors for progression. Prevalence data from this study will be used for estimating the need for medical counseling and rehabilitative services and projecting health care costs. These data are important because of the large numbers of older persons affected. Such epidemiologic data are necessary to describe persons at increased risk and to allow better understanding of possible etiologic relationships.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG011099-02
Application #
2052317
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Project Start
1993-03-15
Project End
1998-02-28
Budget Start
1994-03-01
Budget End
1995-02-28
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
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