Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG011644-04
Application #
2052865
Study Section
Biological and Clinical Aging Review Committee (BCA)
Project Start
1993-09-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Southern California
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Curtis, Christina; Landis, Gary N; Folk, Donna et al. (2007) Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes. Genome Biol 8:R262
Tower, John (2006) Sex-specific regulation of aging and apoptosis. Mech Ageing Dev 127:705-18
Landis, Gary N; Tower, John (2005) Superoxide dismutase evolution and life span regulation. Mech Ageing Dev 126:365-79
Bhole, Deepak; Allikian, Michael J; Tower, John (2004) Doxycycline-regulated over-expression of hsp22 has negative effects on stress resistance and life span in adult Drosophila melanogaster. Mech Ageing Dev 125:651-63
Landis, Gary N; Abdueva, Diana; Skvortsov, Dmitriy et al. (2004) Similar gene expression patterns characterize aging and oxidative stress in Drosophila melanogaster. Proc Natl Acad Sci U S A 101:7663-8
Phelan, John P; Archer, Margaret A; Beckman, Kelly A et al. (2003) Breakdown in correlations during laboratory evolution. I. Comparative analyses of Drosophila populations. Evolution 57:527-35
Archer, Margaret A; Phelan, John P; Beckman, Kelly A et al. (2003) Breakdown in correlations during laboratory evolution. II. Selection on stress resistance in Drosophila populations. Evolution 57:536-43
Landis, Gary N; Bhole, Deepak; Tower, John (2003) A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genes. Genome Biol 4:R8
Sun, Jingtao; Folk, Donna; Bradley, Timothy J et al. (2002) Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster. Genetics 161:661-72
Allikian, Michael J; Deckert-Cruz, Denise; Rose, Michael R et al. (2002) Doxycycline-induced expression of sense and inverted-repeat constructs modulates phosphogluconate mutase (Pgm) gene expression in adult Drosophila melanogaster. Genome Biol 3:research0021

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