We will study change in personality and psychological well-being, and the relationship between such change and physical health, as assessed by self-reports, daily cortisol levels, and mortality. Personality and well being variables can shape the changes in health that mark older age, yet these are often as changing and dynamic as health itself. Thus, studies of change offer an opportunity to gain greater understanding of the psychosocial pathways that lead to good or bad health. We will study change that unfolds over years (Aim 1), as well as change that unfolds over days (Aim 3). In a new aim, we will study whether changes in personality and well-being predict mortality (Aim 2). To do this, we will use existing longitudinal data from the past 40 years of the VA Normative Aging Study (MAS), new data we have collected on these men and their wives in Years 1-5, and new data that we will collect in Years 6-10.
For Aims 2 and 3, we will also utilize the MIDUS II study (P01-AG020166), providing comparisons with national data. We will focus on 3 aims: 1) Model intraindividual change in personality, well-being, and physical health overtime, and examine predictors of change, using individual growth models and coupled-change growth models. 2) Model time to mortality using personality and well-being and their interactions with contextual factors. As of June, 2004, 45 percent of the NAS participants have died, permitting prediction of mortality from hazard rate models. We will also bring together Aims 1 and 2 by using change in personality and well-being to predict mortality. 3) Model daily variation in affect, memory, and cortisol as a function of daily stressors and global personality and wellbeing. We will use """"""""measurement bursts"""""""" of diary studies nested within our longitudinal study to better understand the interplay between daily experience, well-being, personality and biological indicators of stress (cortisol) in older adults. Findings from this study will illuminate how changes in psychosocial variables-at both the multi-year and daily levels-lead to good health, bad health, and mortality.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG018436-09
Application #
7482246
Study Section
Special Emphasis Panel (ZRG1-RPHB-A (08))
Program Officer
Nielsen, Lisbeth
Project Start
2000-09-15
Project End
2010-08-31
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
9
Fiscal Year
2008
Total Cost
$256,648
Indirect Cost
Name
Purdue University
Department
Pediatrics
Type
Other Domestic Higher Education
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907
Massey, Suena H; Mroczek, Daniel K; Reiss, David et al. (2018) Additive drug-specific and sex-specific risks associated with co-use of marijuana and tobacco during pregnancy: Evidence from 3 recent developmental cohorts (2003-2015). Neurotoxicol Teratol 68:97-106
Pearman, Timothy P; Beaumont, Jennifer L; Mroczek, Daniel et al. (2018) Validity and usefulness of a single-item measure of patient-reported bother from side effects of cancer therapy. Cancer 124:991-997
Chiang, Jessica J; Turiano, Nicholas A; Mroczek, Daniel K et al. (2018) Affective reactivity to daily stress and 20-year mortality risk in adults with chronic illness: Findings from the National Study of Daily Experiences. Health Psychol 37:170-178
Weston, Sara J; Hill, Patrick L; Edmonds, Grant W et al. (2018) No Evidence of ""healthy neuroticism"" in the Hawaii Personality and Health Cohort. Ann Behav Med :
Morton, Patricia M; Turiano, Nicholas A; Mroczek, Daniel K et al. (2018) Childhood Misfortune, Personality, and Heart Attack: Does Personality Mediate Risk of Myocardial Infarction? J Gerontol B Psychol Sci Soc Sci 73:825-835
Massey, Suena H; Hatcher, Amalia E; Clark, Caron A C et al. (2017) Does MAOA increase susceptibility to prenatal stress in young children? Neurotoxicol Teratol 61:82-91
Lezotte, Daniel V; Condon, David M; Mroczek, Daniel K (2017) A Call for Cross-Fertilization Among Personality and Personnel Selection Researchers. Eur J Pers 31:468-469
Hostinar, Camelia E; Davidson, Richard J; Graham, Eileen K et al. (2017) Frontal brain asymmetry, childhood maltreatment, and low-grade inflammation at midlife. Psychoneuroendocrinology 75:152-163
Sloan, Richard P; Schwarz, Emilie; McKinley, Paula S et al. (2017) Vagally-mediated heart rate variability and indices of well-being: Results of a nationally representative study. Health Psychol 36:73-81
Graham, Eileen K; Rutsohn, Joshua P; Turiano, Nicholas A et al. (2017) Personality Predicts Mortality Risk: An Integrative Data Analysis of 15 International Longitudinal Studies. J Res Pers 70:174-186

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