RESEARCH GOALS FOR 1979-80: Emphasis will be placed upon the following research problems. a. Function of the non-structural 100K protein in assembly of hexons. b. Characterization of ts mutants of type 7 adenovirus. c. Selection of mutants to reveal the functions of viral proteins required for virion assembly.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI012053-12
Application #
3125097
Study Section
Virology Study Section (VR)
Project Start
1975-09-01
Project End
1987-06-30
Budget Start
1985-07-01
Budget End
1987-06-30
Support Year
12
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
Schools of Medicine
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027
Praszkier, J; Ginsberg, H S (1987) Isolation and characterization of temperature-sensitive mutants of adenovirus type 7. J Virol 61:3089-95
Freimuth, P I; Ginsberg, H S (1986) Codon insertion mutants of the adenovirus terminal protein. Proc Natl Acad Sci U S A 83:7816-20