Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI013725-17
Application #
2060021
Study Section
Immunobiology Study Section (IMB)
Project Start
1977-09-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brandeis University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
616845814
City
Waltham
State
MA
Country
United States
Zip Code
02454
Maul, Robert W; Cao, Zheng; Venkataraman, Lakshmi et al. (2014) Spt5 accumulation at variable genes distinguishes somatic hypermutation in germinal center B cells from ex vivo-activated cells. J Exp Med 211:2297-306
Giorgetti, C A; Press, J L (1998) Somatic mutation in the neonatal mouse. J Immunol 161:6093-104
Mainville, C A; Sheehan, K M; Klaman, L D et al. (1996) Deletional mapping of fifteen mouse VH gene families reveals a common organization for three Igh haplotypes. J Immunol 156:1038-46
Giorgetti, C A; Press, J L (1994) A peptide sequence mimics the epitope on the multideterminant antigen (Tyr,Glu)-Ala-Lys that induces the dominant H10/V kappa 1+ primary antibody response. J Immunol 152:136-45
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Press, J L; Giorgetti, C A; Busby 3rd, W F (1991) A new germline VH36-60 gene is used in the neonatal primary and adult memory response to (T,G)-A--L. Mol Immunol 28:1217-24
Borriero, L; Giorgetti, C; Smith, G et al. (1990) Neonatal and adult primary B cells use the same germ-line VH and V kappa genes in their (T,G)-A-L-specific repertoire. J Immunol 144:583-92
Busto, P; Gerstein, R; Dupre, L et al. (1987) Molecular analysis of heavy and light chains used by primary and secondary anti-(T,G)-A--L antibodies produced by normal and xid mice. J Immunol 139:608-18
Press, J L; Giorgetti, C A (1986) Clonal analysis of the primary and secondary B cell responses of neonatal, adult, and xid mice to (T,G)-A--L. J Immunol 137:784-90
Busto, P; Giorgetti, C A; Gawoski, J et al. (1986) Xid and normal mice express a light chain-associated cross-reactive idiotype in response to (T,G)-A--L and (T,G)-A--L-mBSA. J Immunol 136:3734-43