Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI014584-38
Application #
6757196
Study Section
Allergy and Immunology Study Section (ALY)
Program Officer
Kirkham, Perry M
Project Start
1978-01-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
38
Fiscal Year
2004
Total Cost
$401,575
Indirect Cost
Name
Johns Hopkins University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Boyle, Sarah; Kolin, David L; Bieler, Joan Glick et al. (2011) Quantum dot fluorescence characterizes the nanoscale organization of T cell receptors for antigen. Biophys J 101:L57-9
Edidin, Michael (2010) Class I MHC molecules as probes of membrane patchiness: from biophysical measurements to modulation of immune responses. Immunol Res 47:265-72
Abe, Fumiyoshi; Van Prooyen, Nancy; Ladasky, John J et al. (2009) Interaction of Bap31 and MHC class I molecules and their traffic out of the endoplasmic reticulum. J Immunol 182:4776-83
Shaikh, Saame Raza; Boyle, Sarah; Hua, Jing et al. (2009) In vivo test of the vertical phase separation hypothesis: the display of major histocompatibility complex (MHC) class I molecules on membranes of B cells from mice fed high-fat diets. Br J Nutr 101:804-9
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Fooksman, David Robert; Shaikh, Saame Raza; Boyle, Sarah et al. (2009) Cutting edge: phosphatidylinositol 4,5-bisphosphate concentration at the APC side of the immunological synapse is required for effector T cell function. J Immunol 182:5179-82
Weaver, Frances E; Shaikh, Saame Raza; Edidin, Michael (2008) Plasma membrane lipid diffusion and composition of sea urchin egg membranes vary with ocean temperature. Chem Phys Lipids 151:62-5
Shaikh, S R; Mitchell, D; Carroll, E et al. (2008) Differential effects of a saturated and a monounsaturated fatty acid on MHC class I antigen presentation. Scand J Immunol 68:30-42
Shaikh, Saame Raza; Edidin, Michael (2008) Polyunsaturated fatty acids and membrane organization: elucidating mechanisms to balance immunotherapy and susceptibility to infection. Chem Phys Lipids 153:24-33
Lavi, Yael; Edidin, Michael A; Gheber, Levi A (2007) Dynamic patches of membrane proteins. Biophys J 93:L35-7

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