Abstract

Juvenile hormone (JH) plays a major role in regulation of larval development and adult reproduction in insects. The long term gaol of this research is to understand the regulation of JH synthesis by the corpora allata (CA). The experimental system is the female reproductive cycle of the cockroach Diploptera punctata.
The Specific Aims are to demonstrate: 1) The degree to which allatostatins, neuropeptides that inhibit JH synthesis, regulate JH synthesis during the reproductive cycle; 2) to determine whether the ovary acts on JH production through allatostatin and/or independently; 3) to study how allatostatins act on the CA; 4) to search for stimulatory neuropeptides, allatotropins.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI015230-20
Application #
2886373
Study Section
Special Emphasis Panel (ZRG5-TMP (01))
Program Officer
Aultman, Kathryn S
Project Start
1979-05-01
Project End
2001-03-14
Budget Start
1999-08-01
Budget End
2001-03-14
Support Year
20
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of Iowa
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242

  Publications

Elliott, Karen L; Woodhead, Andrea P; Stay, Barbara (2006) A stage-specific ovarian factor with stable stimulation of juvenile hormone synthesis in corpora allata of the cockroach Diploptera punctata. J Insect Physiol 52:929-35
Woodhead, A P; Thompson, M E; Chan, K K et al. (2003) Allatostatin in ovaries, oviducts, and young embryos in the cockroach Diploptera punctata. J Insect Physiol 49:1103-14
Rudolph, P H; Stay, B (1997) Cockroach allatostatin-like immunoreactivity in the central nervous system of the freshwater snails Bulinus globosus (Planorbidae) and Stagnicola elodes (Lymnaeidae). Gen Comp Endocrinol 106:241-50
Stay, B; Fairbairn, S; Yu, C G (1996) Role of allatostatins in the regulation of juvenile hormone synthesis. Arch Insect Biochem Physiol 32:287-97
Lange, A B; Chan, K K; Stay, B (1993) Effect of allatostatin and proctolin on antennal pulsatile organ and hindgut muscle in the cockroach, Diploptera punctata. Arch Insect Biochem Physiol 24:79-92
Johnson, G D; Stay, B; Chan, K K (1993) Structure-activity relationships in corpora allata of the cockroach Diploptera punctata: roles of mating and the ovary. Cell Tissue Res 274:279-93
Woodhead, A P; Stoltzman, C A; Stay, B (1992) Allatostatins in the nerves of the antennal pulsatile organ muscle of the cockroach Diploptera punctata. Arch Insect Biochem Physiol 20:253-63
Stay, B; Chan, K K; Woodhead, A P (1992) Allatostatin-immunoreactive neurons projecting to the corpora allata of adult Diploptera punctata. Cell Tissue Res 270:15-23
Stay, B; Woodhead, A P (1990) Response of male corpora allata to ovarian stimulation in the cockroach, Diploptera punctata. Gen Comp Endocrinol 77:127-35
Rankin, S M; Stay, B (1985) Ovarian inhibition of juvenile hormone synthesis in the viviparous cockroach, Diploptera punctata. Gen Comp Endocrinol 59:230-7

Showing the most recent 10 out of 11 publications