Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
7R01AI018449-11
Application #
3127955
Study Section
Virology Study Section (VR)
Project Start
1982-08-01
Project End
1995-08-31
Budget Start
1992-01-31
Budget End
1992-08-31
Support Year
11
Fiscal Year
1991
Total Cost
Indirect Cost
Name
State University of New York at Buffalo
Department
Type
Schools of Dentistry
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Khalil, Mohamed I; Che, Xibing; Sung, Phillip et al. (2016) Mutational analysis of varicella-zoster virus (VZV) immediate early protein (IE62) subdomains and their importance in viral replication. Virology 492:82-91
Khalil, Mohamed I; Sommer, Marvin H; Hay, John et al. (2015) Varicella-zoster virus (VZV) origin of DNA replication oriS influences origin-dependent DNA replication and flanking gene transcription. Virology 481:179-86
Khalil, Mohamed I; Ruyechan, William T; Hay, John et al. (2015) Differential effects of Sp cellular transcription factors on viral promoter activation by varicella-zoster virus (VZV) IE62 protein. Virology 485:47-57
Khalil, Mohamed I; Sommer, Marvin; Arvin, Ann et al. (2014) Cellular transcription factor YY1 mediates the varicella-zoster virus (VZV) IE62 transcriptional activation. Virology 449:244-53
Khalil, Mohamed I; Sommer, Marvin; Arvin, Ann et al. (2013) Regulation of the varicella-zoster virus ORF3 promoter by cellular and viral factors. Virology 440:171-81
Khalil, Mohamed I; Robinson, Makeda; Sommer, Marvin et al. (2012) An Sp1/Sp3 site in the downstream region of varicella-zoster virus (VZV) oriS influences origin-dependent DNA replication and flanking gene transcription and is important for VZV replication in vitro and in human skin. J Virol 86:13070-80
Eletsky, Alexander; Ruyechan, William T; Xiao, Rong et al. (2011) Solution NMR structure of MED25(391-543) comprising the activator-interacting domain (ACID) of human mediator subunit 25. J Struct Funct Genomics 12:159-66
Khalil, Mohamed I; Arvin, Ann; Jones, Jeremy et al. (2011) A sequence within the varicella-zoster virus (VZV) OriS is a negative regulator of DNA replication and is bound by a protein complex containing the VZV ORF29 protein. J Virol 85:12188-200
Ruyechan, William T (2010) Roles of cellular transcription factors in VZV replication. Curr Top Microbiol Immunol 342:43-65
White, Kris; Peng, Hua; Hay, John et al. (2010) Role of the IE62 consensus binding site in transactivation by the varicella-zoster virus IE62 protein. J Virol 84:3767-79

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