Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI018988-12
Application #
2060832
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1984-03-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Cameron, C E; Castro, C; Lukehart, S A et al. (1999) Sequence conservation of glycerophosphodiester phosphodiesterase among Treponema pallidum strains. Infect Immun 67:3168-70
Centurion-Lara, A; Castro, C; Barrett, L et al. (1999) Treponema pallidum major sheath protein homologue Tpr K is a target of opsonic antibody and the protective immune response. J Exp Med 189:647-56
Centurion-Lara, A; Castro, C; Castillo, R et al. (1998) The flanking region sequences of the 15-kDa lipoprotein gene differentiate pathogenic treponemes. J Infect Dis 177:1036-40
Cameron, C E; Castro, C; Lukehart, S A et al. (1998) Function and protective capacity of Treponema pallidum subsp. pallidum glycerophosphodiester phosphodiesterase. Infect Immun 66:5763-70
Centurion-Lara, A; Castro, C; Shaffer, J M et al. (1997) Detection of Treponema pallidum by a sensitive reverse transcriptase PCR. J Clin Microbiol 35:1348-52
Stebeck, C E; Shaffer, J M; Arroll, T W et al. (1997) Identification of the Treponema pallidum subsp. pallidum glycerophosphodiester phosphodiesterase homologue. FEMS Microbiol Lett 154:303-10
Centurion-Lara, A; Arroll, T; Castillo, R et al. (1997) Conservation of the 15-kilodalton lipoprotein among Treponema pallidum subspecies and strains and other pathogenic treponemes: genetic and antigenic analyses. Infect Immun 65:1440-4
Marra, C M; Longstreth Jr, W T; Maxwell, C L et al. (1996) Resolution of serum and cerebrospinal fluid abnormalities after treatment of neurosyphilis. Influence of concomitant human immunodeficiency virus infection. Sex Transm Dis 23:184-9
Van Voorhis, W C; Barrett, L K; Koelle, D M et al. (1996) Primary and secondary syphilis lesions contain mRNA for Th1 cytokines. J Infect Dis 173:491-5
Centurion-Lara, A; Castro, C; van Voorhis, W C et al. (1996) Two 16S-23S ribosomal DNA intergenic regions in different Treponema pallidum subspecies contain tRNA genes. FEMS Microbiol Lett 143:235-40

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