Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI020325-10
Application #
3129926
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1984-04-01
Project End
1993-07-31
Budget Start
1993-05-01
Budget End
1993-07-31
Support Year
10
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111
Fuchs, S; Muhldorfer, I; Donohue-Rolfe, A et al. (1999) Influence of RecA on in vivo virulence and Shiga toxin 2 production in Escherichia coli pathogens. Microb Pathog 27:13-23
Gunzer, F; Bohn, U; Fuchs, S et al. (1998) Construction and characterization of an isogenic slt-ii deletion mutant of enterohemorrhagic Escherichia coli. Infect Immun 66:2337-41
Muhldorfer, I; Hacker, J; Keusch, G T et al. (1996) Regulation of the Shiga-like toxin II operon in Escherichia coli. Infect Immun 64:495-502
Tzipori, S; Gunzer, F; Donnenberg, M S et al. (1995) The role of the eaeA gene in diarrhea and neurological complications in a gnotobiotic piglet model of enterohemorrhagic Escherichia coli infection. Infect Immun 63:3621-7
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Donta, S T; Tomicic, T K; Donohue-Rolfe, A (1995) Inhibition of Shiga-like toxins by brefeldin A. J Infect Dis 171:721-4
Jacewicz, M S; Acheson, D W; Mobassaleh, M et al. (1995) Maturational regulation of globotriaosylceramide, the Shiga-like toxin 1 receptor, in cultured human gut epithelial cells. J Clin Invest 96:1328-35
Keusch, G T; Jacewicz, M; Acheson, D W et al. (1995) Globotriaosylceramide, Gb3, is an alternative functional receptor for Shiga-like toxin 2e. Infect Immun 63:1138-41
Acheson, D W; Jacewicz, M; Kane, A V et al. (1993) One step high yield affinity purification of shiga-like toxin II variants and quantitation using enzyme linked immunosorbent assays. Microb Pathog 14:57-66
Acheson, D W (1992) Enterotoxins in acute infective diarrhoea. J Infect 24:225-45

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