This research program is directed toward the total synthesis of the natural product ikarugamycin. Ikarugamycin has demonstrated activity against gram positive bacteria and against amoeba. The synthetic plan involves several novel transformations that will provide new synthetic methods useful in general for the construction of complex, biologically active compounds.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI020357-03
Application #
3129976
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1983-07-01
Project End
1986-06-30
Budget Start
1985-07-01
Budget End
1986-06-30
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Texas Austin
Department
Type
Schools of Arts and Sciences
DUNS #
City
Austin
State
TX
Country
United States
Zip Code
78713