Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI020486-13
Application #
2061239
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1983-04-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rosalind Franklin University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
069501252
City
North Chicago
State
IL
Country
United States
Zip Code
60064
Dutta, Sujoy; Chang, Celia; Kolli, Bala Krishna et al. (2012) Delta-aminolevulinate-induced host-parasite porphyric disparity for selective photolysis of transgenic Leishmania in the phagolysosomes of mononuclear phagocytes: a potential novel platform for vaccine delivery. Eukaryot Cell 11:430-41
Mehta, Sanjay R; Zhang, Xing-Quan; Badaro, Roberto et al. (2010) Flow cytometric screening for anti-leishmanials in a human macrophage cell line. Exp Parasitol 126:617-20
Varela M, Ruben E; Munoz, Diana Lorena; Robledo, Sara M et al. (2009) Leishmania (Viannia) panamensis: an in vitro assay using the expression of GFP for screening of antileishmanial drug. Exp Parasitol 122:134-9
Mehta, Sanjay R; Huang, Robert; Yang, Meng et al. (2008) Real-time in vivo green fluorescent protein imaging of a murine leishmaniasis model as a new tool for Leishmania vaccine and drug discovery. Clin Vaccine Immunol 15:1764-70
Kolli, Bala Krishna; Kostal, Jan; Zaborina, Olga et al. (2008) Leishmania-released nucleoside diphosphate kinase prevents ATP-mediated cytolysis of macrophages. Mol Biochem Parasitol 158:163-75
Dutta, Sujoy; Furuyama, Kazumichi; Sassa, Shigeru et al. (2008) Leishmania spp.: delta-aminolevulinate-inducible neogenesis of porphyria by genetic complementation of incomplete heme biosynthesis pathway. Exp Parasitol 118:629-36
Dutta, Sujoy; Kolli, Bala Krishna; Tang, Aihua et al. (2008) Transgenic Leishmania model for delta-aminolevulinate-inducible monospecific uroporphyria: cytolytic phototoxicity initiated by singlet oxygen-mediated inactivation of proteins and its ablation by endosomal mobilization of cytosolic uroporphyrin. Eukaryot Cell 7:1146-57
Waki, Kayoko; Dutta, Sujoy; Ray, Debalina et al. (2007) Transmembrane molecules for phylogenetic analyses of pathogenic protists: Leishmania-specific informative sites in hydrophilic loops of trans- endoplasmic reticulum N-acetylglucosamine-1-phosphate transferase. Eukaryot Cell 6:198-210
Thiakaki, Maria; Kolli, Bala; Chang, Kwang-Poo et al. (2006) Down-regulation of gp63 level in Leishmania amazonensis promastigotes reduces their infectivity in BALB/c mice. Microbes Infect 8:1455-63
Dutta, Sujoy; Ray, Debalina; Kolli, Bala K et al. (2005) Photodynamic sensitization of Leishmania amazonensis in both extracellular and intracellular stages with aluminum phthalocyanine chloride for photolysis in vitro. Antimicrob Agents Chemother 49:4474-84

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