Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI020530-13
Application #
2061259
Study Section
Experimental Virology Study Section (EVR)
Project Start
1983-12-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1998-04-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Johnson, Karen E; Song, Byeongwoon; Knipe, David M (2008) Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling. Virology 374:487-94
Fontaine-Rodriguez, Errin C; Knipe, David M (2008) Herpes simplex virus ICP27 increases translation of a subset of viral late mRNAs. J Virol 82:3538-45
Melroe, Gregory T; Silva, Lindsey; Schaffer, Priscilla A et al. (2007) Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction. Virology 360:305-21
Olesky, Melanie; McNamee, Elizabeth E; Zhou, Changhong et al. (2005) Evidence for a direct interaction between HSV-1 ICP27 and ICP8 proteins. Virology 331:94-105
Kurt-Jones, Evelyn A; Chan, Melvin; Zhou, Shenghua et al. (2004) Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis. Proc Natl Acad Sci U S A 101:1315-20
Fontaine-Rodriguez, Errin C; Taylor, Travis J; Olesky, Melanie et al. (2004) Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors. Virology 330:487-92
Melroe, Gregory T; DeLuca, Neal A; Knipe, David M (2004) Herpes simplex virus 1 has multiple mechanisms for blocking virus-induced interferon production. J Virol 78:8411-20
Pearson, Angela; Knipe, David M; Coen, Donald M (2004) ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells. J Virol 78:23-32
Zhou, Changhong; Knipe, David M (2002) Association of herpes simplex virus type 1 ICP8 and ICP27 proteins with cellular RNA polymerase II holoenzyme. J Virol 76:5893-904
Song, B; Yeh, K C; Liu, J et al. (2001) Herpes simplex virus gene products required for viral inhibition of expression of G1-phase functions. Virology 290:320-8

Showing the most recent 10 out of 33 publications