Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI020943-12S1
Application #
2003298
Study Section
Pathology A Study Section (PTHA)
Project Start
1984-09-30
Project End
1996-12-31
Budget Start
1996-09-01
Budget End
1996-12-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Connecticut
Department
Pathology
Type
Schools of Dentistry
DUNS #
City
Farmington
State
CT
Country
United States
Zip Code
06030
Wu, Yue; Zhan, Lijun; Ai, Youxi et al. (2007) MAPKAPK2-mediated LSP1 phosphorylation and FMLP-induced neutrophil polarization. Biochem Biophys Res Commun 358:170-5
Hannigan, Michael; Zhan, Lijun; Li, Zhong et al. (2002) Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis. Proc Natl Acad Sci U S A 99:3603-8
Mathews, Clayton E; Dunn, Brian D; Hannigan, Michael O et al. (2002) Genetic control of neutrophil superoxide production in diabetes-resistant ALR/Lt mice. Free Radic Biol Med 32:744-51
Hannigan, M O; Zhan, L; Ai, Y et al. (2001) Abnormal migration phenotype of mitogen-activated protein kinase-activated protein kinase 2-/- neutrophils in Zigmond chambers containing formyl-methionyl-leucyl-phenylalanine gradients. J Immunol 167:3953-61
Hannigan, M; Zhan, L; Ai, Y et al. (2001) Leukocyte-specific gene 1 protein (LSP1) is involved in chemokine KC-activated cytoskeletal reorganization in murine neutrophils in vitro. J Leukoc Biol 69:497-504
Huang, C K; Zhan, L; Hannigan, M O et al. (2000) P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+. J Leukoc Biol 67:210-5
Zu, Y L; Qi, J; Gilchrist, A et al. (1998) p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation. J Immunol 160:1982-9
Hannigan, M; Zhan, L; Ai, Y et al. (1998) The role of p38 MAP kinase in TGF-beta1-induced signal transduction in human neutrophils. Biochem Biophys Res Commun 246:55-8
Huang, C K; Zhan, L; Ai, Y et al. (1997) LSP1 is the major substrate for mitogen-activated protein kinase-activated protein kinase 2 in human neutrophils. J Biol Chem 272:17-9
Zu, Y L; Ai, Y; Gilchrist, A et al. (1997) High expression and activation of MAP kinase-activated protein kinase 2 in cardiac muscle cells. J Mol Cell Cardiol 29:2159-68

Showing the most recent 10 out of 40 publications