Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI020958-12
Application #
2061372
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1984-04-01
Project End
1996-05-31
Budget Start
1996-04-01
Budget End
1996-05-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Yang, Ri-Yao; Xue, Huiting; Yu, Lan et al. (2016) Identification of VPS13C as a Galectin-12-Binding Protein That Regulates Galectin-12 Protein Stability and Adipogenesis. PLoS One 11:e0153534
Chung, Andrew W; Sieling, Peter A; Schenk, Mirjam et al. (2013) Galectin-3 regulates the innate immune response of human monocytes. J Infect Dis 207:947-56
Choy, David F; Hsu, Daniel K; Seshasayee, Dhaya et al. (2012) Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation. J Allergy Clin Immunol 130:1335-43.e5
Yang, Ri-Yao; Yu, Lan; Graham, James L et al. (2011) Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice. Proc Natl Acad Sci U S A 108:18696-701
Larsen, Larissa; Chen, Huan-Yuan; Saegusa, Jun et al. (2011) Galectin-3 and the skin. J Dermatol Sci 64:85-91
Markowska, Anna I; Liu, Fu-Tong; Panjwani, Noorjahan (2010) Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response. J Exp Med 207:1981-93
Deng, Zhao; Zink, Tiffany; Chen, Huan-yuan et al. (2009) Impact of actin rearrangement and degranulation on the membrane structure of primary mast cells: a combined atomic force and laser scanning confocal microscopy investigation. Biophys J 96:1629-39
Chen, Huan-Yuan; Fermin, Agnes; Vardhana, Santosh et al. (2009) Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. Proc Natl Acad Sci U S A 106:14496-501
Saegusa, Jun; Hsu, Daniel K; Chen, Huan-Yuan et al. (2009) Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis. Am J Pathol 174:922-31
Hsu, Daniel K; Chernyavsky, Alexander I; Chen, Huan-Yuan et al. (2009) Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells. J Invest Dermatol 129:573-83

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